Alhomoud Mohsen Ali, Gosadi Ibrahim M, Wahbi Hayfaa A
Department of Preventive Medicine, Ministry of Health, Eastern Province, King Saud University, Riyadh, Saudi Arabia.
Department of Family and Community Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Saudi J Med Med Sci. 2018 Jan-Apr;6(1):8-12. doi: 10.4103/sjmms.sjmms_123_16. Epub 2017 Dec 14.
To determine the prevalence of, and factors associated with, depression among sickle cell anemia adult patients in the Eastern Province of Saudi Arabia.
A cross-sectional study was conducted between December 2014 and May 2015 among sickle cell anemia patients aged 16-70 years from the outpatient hematology clinics at Qatif Central Hospital. A total of 110 successive participants consented and answered an anonymous, self-administered, questionnaire and the Arabic version of the Beck Depression Inventory-II. Individuals were considered depressed if they scored ≥14 in Beck Depression Inventory-II. Simple logistic regression was used to compare differences between the depressed and nondepressed groups. Odds ratios (ORs) with 95% confidence intervals (95% CI) were reported.
Depression was detected in 53 participants (48.2%). Bivariate analysis showed that lower educational qualification (OR = 2.5; 95% CI = 1.1-5.3; = 0.021), higher frequency of vaso-occlusive crises (OR = 3.4; 95% CI = 1.3-8.7; = 0.008) and frequent visits to the hematology clinic (OR = 5.3; 95% CI = 1.4-19.9; = 0.008) were significantly associated with depression.
This study revealed that there is high prevalence of depression among sickle cell anemia patients in the Eastern Province of Saudi Arabia.
确定沙特阿拉伯东部省镰状细胞贫血成年患者中抑郁症的患病率及其相关因素。
2014年12月至2015年5月，在卡提夫中心医院门诊血液科对16 - 70岁的镰状细胞贫血患者进行了一项横断面研究。共有110名连续参与者同意并回答了一份匿名的自填式问卷以及贝克抑郁量表第二版的阿拉伯语版本。如果个体在贝克抑郁量表第二版中的得分≥14分，则被认为患有抑郁症。采用简单逻辑回归比较抑郁组和非抑郁组之间的差异。报告了比值比（OR）及其95%置信区间（95%CI）。
53名参与者（48.2%）被检测出患有抑郁症。二元分析显示，较低的教育程度（OR = 2.5；95%CI = 1.1 - 5.3；P = 0.021）、较高频率的血管闭塞性危机（OR = 3.4；95%CI = 1.3 - 8.7；P = 0.008）以及频繁前往血液科就诊（OR = 5.3；95%CI = 1.4 - 19.9；P = 0.008）与抑郁症显著相关。
本研究表明，沙特阿拉伯东部省镰状细胞贫血患者中抑郁症的患病率很高。
