Sundar Chalini, Ramalingam Sundar, Mohan Viswanathan, Pradeepa Rajendra, Ramakrishnan M J
Department of Dental Public Health, Identiti Dental Centre, Chennai, Tamil Nadu, India.
Department of Research Support, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
J Educ Health Promot. 2018 Dec 28;7:152. doi: 10.4103/jehp.jehp_66_18. eCollection 2018.
This study aimed to evaluate the role of nonsurgical periodontal therapy in improving glycemic control among type 2 diabetes mellitus (T2DM) patients.
Adult T2DM patients with mild-to-moderate periodontal disease, reporting to a tertiary care diabetes center in South India, from January to June 2014, were enrolled in the study. Medical management of T2DM along with diet and physical exercise was an inclusion criterion. Patients with factors affecting periodontal health and an inability to follow-up were excluded from the study. All patients underwent nonsurgical periodontal therapy (scaling, root planing, and irrigation of chlorhexidine [0.12%]). Periodontal status and glycated hemoglobin A1c (HbA1c) were assessed preoperatively and 6 months posttreatment. Dental status, diabetic history, and demographic characteristics were recorded to evaluate confounding roles.
A total of 266 T2DM patients (91 females/175 males; mean age 47.65 ± 5.93 years/range 25-55 years), fulfilling the inclusion criteria, were enrolled. The mean pre- and post-treatment HbA1c levels were respectively, 8.44 ± 1.87 and 7.98 ± 1.81, with a mean reduction of 0.46 ± 0.26 ( < 0.001). Significant HbA1c reduction ( < 0.001) was observed in patients with good pretreatment glycemic control (0.54 ± 0.26; 7.9%), regular follow-up (0.51 ± 0.28; 6.2%), and good oral hygiene (0.60 ± 0.49; 8.0%).
Nonsurgical periodontal therapy is associated with significant HbA1c reduction among T2DM patients with mild-to-moderate periodontitis after a 6-month follow-up period.
本研究旨在评估非手术牙周治疗在改善2型糖尿病(T2DM)患者血糖控制方面的作用。
2014年1月至6月期间,前往印度南部一家三级护理糖尿病中心就诊的患有轻至中度牙周病的成年T2DM患者被纳入本研究。T2DM的药物治疗以及饮食和体育锻炼是纳入标准。排除有影响牙周健康因素和无法进行随访的患者。所有患者均接受非手术牙周治疗(龈上洁治、根面平整以及0.12%洗必泰冲洗)。在术前和治疗后6个月评估牙周状况和糖化血红蛋白A1c(HbA1c)。记录牙齿状况、糖尿病病史和人口统计学特征以评估混杂因素的作用。
共有266名符合纳入标准的T2DM患者(91名女性/175名男性;平均年龄47.65±5.93岁/范围25 - 55岁)被纳入研究。治疗前和治疗后HbA1c的平均水平分别为8.44±1.87和7.98±1.81,平均降低0.46±0.26(<0.001)。在治疗前血糖控制良好(0.54±0.26;7.9%)、定期随访(0.51±0.28;6.2%)以及口腔卫生良好(0.60±0.49;8.0%)的患者中观察到HbA1c显著降低(<0.001)。
经过6个月的随访期,非手术牙周治疗与轻至中度牙周炎的T2DM患者HbA1c显著降低相关。