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采用骨整合经皮假体治疗拇指截肢并进行长达25年的随访。

Thumb Amputations Treated With Osseointegrated Percutaneous Prostheses With Up to 25 Years of Follow-up.

作者信息

Li Yan, Kulbacka-Ortiz Katarzyna, Caine-Winterberger Kerstin, Brånemark Rickard

机构信息

Trauma and Reparative Medicine Theme, Karolinska University Hospital, Solna, Sweden (Dr. Li); the Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden (Dr. Li); the Centre for Advanced Reconstruction of Extremities (C.A.R.E.), Sahlgrenska University Hospital, Gothenburg, Sweden (Ms. Kulbacka and Ms. Caine-Winterberge); and the Department of Orthopaedics, International Centre for Osseointegration Research, Education and Surgery (iCORES), University of California, San Francisco, CA (Dr. Brånemark); and the Department of Orthopaedics, Gothenburg University, Gothenburg, Sweden (Dr. Brånemark).

出版信息

J Am Acad Orthop Surg Glob Res Rev. 2019 Jan 23;3(1):e097. doi: 10.5435/JAAOSGlobal-D-18-00097. eCollection 2019 Jan.

Abstract

INTRODUCTION

Implantation of an osseointegrated percutaneous prosthesis provides a reconstruction alternative for thumb amputation without sacrificing donor tissues.

METHODS

Thirteen thumb amputees received osseointegrated prostheses (1990 to 2014). The treatments were started with custom-designed implants. Since 2005, standardized implant components and structured rehabilitation protocols were introduced. The median follow-up period was 9.5 years.

RESULTS

Six patients were lost to follow-up. Seven patients (including all six after the introduction of the standardized protocol) had good osseoperception, grip strength (Jamar) was 28.3 kg on the operated side versus 40.4 kg in the unaffected hand (70%), and key grip strength was 6 versus 9.1 kg. Hand function was 94% of the normal hand. The most common complications were mechanical failures necessitating changes of components (eight times in three patients) and superficial infections (seven times in five patients). Five patients had no complications. The refined implant design and new standardized treatment protocol achieved a 100% cumulative success rate with 9.5 years of follow-up so far.

DISCUSSION

Treatment of thumb amputees using bone-anchored percutaneous prostheses seems to be a safe, durable method with excellent short- and medium-long follow-up results. Severe adverse events are few except for implant loosening which occurred only in the early custom-designed group.

摘要

引言

植入骨整合经皮假体为拇指截肢提供了一种无需牺牲供体组织的重建替代方案。

方法

13例拇指截肢患者接受了骨整合假体植入(1990年至2014年)。治疗从定制设计的植入物开始。自2005年起,引入了标准化的植入物组件和结构化康复方案。中位随访期为9.5年。

结果

6例患者失访。7例患者(包括引入标准化方案后的所有6例)骨感知良好,患侧握力(Jamar)为28.3千克,健侧为40.4千克(70%),关键握力分别为6千克和9.1千克。手部功能为正常手的94%。最常见的并发症是需要更换组件的机械故障(3例患者共8次)和浅表感染(5例患者共7次)。5例患者无并发症。经过改进的植入物设计和新的标准化治疗方案在迄今9.5年的随访中累积成功率达到100%。

讨论

使用骨锚定经皮假体治疗拇指截肢患者似乎是一种安全、持久的方法,短期和中长期随访结果良好。除了仅在早期定制设计组中出现的植入物松动外,严重不良事件很少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b959/6365303/dffc120559c1/rev-3-e097-g002.jpg

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