多发性硬化症患者中的E玫瑰花结形成淋巴细胞。对玫瑰花结形成细胞的碱性蛋白刺激。
E rosette-forming lymphocytes in multiple sclerosis patients. Basic protein stimulation of rosette-forming cells.
作者信息
Offner H, Konat G, Raun N E, Clausen J
出版信息
Acta Neurol Scand. 1978 May;57(5):380-4. doi: 10.1111/j.1600-0404.1978.tb02841.x.
"Total" and "active" T cells were enumerated using sheep red blood cell (SRBC) rosetting technique. The percentages of "total" and "active" T lymphocytes were not significantly different in multiple sclerosis patients as compared to other neurological disorders and/or healthy controls. However, the number of "avid" T cells binding more than three SRBC was significantly increased in MS patients. Active E rosette test has shown hypersensitization to myelin basic protein in 50% MS patients and 31% OND patients. All healthy controls studied, except one had negative response.
使用绵羊红细胞（SRBC）玫瑰花结技术对“总”T细胞和“活性”T细胞进行计数。与其他神经系统疾病和/或健康对照相比，多发性硬化症患者中“总”T淋巴细胞和“活性”T淋巴细胞的百分比无显著差异。然而，与三个以上SRBC结合的“avid”T细胞数量在MS患者中显著增加。活性E玫瑰花结试验显示，50%的MS患者和31%的其他神经系统疾病（OND）患者对髓鞘碱性蛋白过敏。除一名健康对照外，所有研究的健康对照均呈阴性反应。
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