Traynor Michael D, Hernandez Matthew C, Shariq Omair, Bekker Wanda, Bruce John L, Habermann Elizabeth B, Glasgow Amy E, Laing Grant L, Kong Victor Y, Buitendag Johan J P, Klinkner Denise B, Moir Christopher, Clarke Damian L, Zielinski Martin D, Polites Stephanie F
Division of Trauma, Critical Care, and General Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Division of Health Care Policy and Research, Mayo Clinic, Rochester, MN, USA.
Pediatr Surg Int. 2019 Jun;35(6):699-708. doi: 10.1007/s00383-019-04453-w. Epub 2019 Feb 21.
There is a lack of data-driven, risk-adjusted mortality estimates for injured children outside of high-income countries (HIC). To inform injury prevention and quality improvement efforts, an upper middle-income country (UMIC) pediatric trauma registry was compared to that of a HIC.
Clinical data, injury details, and mortality of injured children (< 18 years) hospitalized in two centers (USA and South African (SA)) from 2013 to 2017 were abstracted. Univariate and multivariable analyses evaluated risk of mortality and were expressed as odds ratios (OR) with 95% confidence intervals (CI).
Of 2089 patients, SA patients had prolonged transfer times (21.1 vs 3.4 h) and were more likely referred (78.2% vs 53.9%; both p < 0.001). Penetrating injuries were more frequent in SA (23.2% vs 7.4%, p < 0.001); injury severity (9 vs 4) and shock index (0.90 vs 0.80) were greater (both p < 0.001). SA utilized cross-sectional imaging more frequently (66.4% vs 37.3%, p < 0.001). In-hospital mortality was similar (1.9% SA, 1.3% USA, p = 0.31). Upon multivariable analysis, ISS > 25 [210.50 (66.0-671.0)] and penetrating injury [5.5 (1.3-23.3)] were associated with mortality, while institution [1.7 (0.7-4.2)] was not.
Despite transfer time, the centers demonstrated comparable survival rates. Comparison of registry data can alert clinicians to problematic practice patterns, assisting initiatives to improve trauma systems.
在高收入国家(HIC)以外,缺乏针对受伤儿童的数据驱动型、风险调整后的死亡率估计。为了为伤害预防和质量改进工作提供信息,将一个中高收入国家(UMIC)的儿科创伤登记数据与一个高收入国家的进行了比较。
提取了2013年至2017年在两个中心(美国和南非(SA))住院的受伤儿童(<18岁)的临床数据、损伤细节和死亡率。单变量和多变量分析评估了死亡风险,并以95%置信区间(CI)的比值比(OR)表示。
在2089例患者中,南非患者的转运时间较长(21.1小时对3.4小时),转诊的可能性更大(78.2%对53.9%;均p<0.001)。穿透性损伤在南非更常见(23.2%对7.4%,p<0.001);损伤严重程度(9对4)和休克指数(0.90对0.80)更高(均p<0.001)。南非更频繁地使用横断面成像(66.4%对37.3%,p<0.001)。住院死亡率相似(南非为1.9%,美国为1.3%,p=0.31)。多变量分析显示,损伤严重度评分(ISS)>25[210.50(66.0-671.0)]和穿透性损伤[5.5(1.3-23.3)]与死亡率相关,而医疗机构[1.7(0.7-4.2)]则无关。
尽管转运时间不同,但两个中心的生存率相当。登记数据的比较可以提醒临床医生注意有问题的实践模式,有助于改进创伤系统的举措。