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肯尼亚部分地区蛇咬伤的流行病学情况。

Epidemiology of snake bites in selected areas of Kenya.

作者信息

Ochola Francis Okumu, Okumu Mitchel Otieno, Muchemi Gerald Mwangi, Mbaria James Mucunu, Gikunju Joseph Kangangi

机构信息

Department of Pharmacology and Toxicology, School of Medicine, Moi University, Eldoret, Kenya.

Department of Pharmacy, Jaramogi Oginga Odinga Teaching and Referral Hospital, Kisumu, Kenya.

出版信息

Pan Afr Med J. 2018 Apr 20;29:217. doi: 10.11604/pamj.2018.29.217.15366. eCollection 2018.

Abstract

INTRODUCTION

Snake bites are a silent public health problem in Kenya. Previous studies on snake bites in the country have mainly focused on identifying offending snake species, assessing the severity of envenomation and testing the efficacy of antivenom. Factors associated with snake bites in the country are yet to be fully understood. The aim of this work was to determine pharmaco-epidemiological factors associated with snake bites in areas of Kenya where incidence, severity and species responsible for snake bites have been reported.

METHODS

Kakamega provincial hospital, Kabarnet, Kapenguria and, Makueni district hospitals were selected as study sites based on previous findings on incidence, severity and species responsible for snake bites in catchment areas of these hospitals. Persistent newspaper reports of snake bites in these areas and distribution of snakes in Kenya were also considered. Cases of snake bites reported between 2007-2009 were retrospectively reviewed and data on incidence, age, site of the bites, time of bite and antivenom use was collected.

RESULTS

176 bites were captured, 91 of which occurred in 2009. Individual incidence was between 2.7/100,000/year and 6.7/100,000/year. Bites peaked in the 1-15 year age group while 132/176 bites were in the lower limb area and 49/176 victims received antivenom. Most bites occurred during the dry season, in the bush and in the evening. Overall mortality was 2.27%.

CONCLUSION

There is a need to sensitize the Kenyan public and healthcare personnel on preventive measures, first aid and treatment of snake bites.

摘要

引言

在肯尼亚,蛇咬伤是一个隐匿的公共卫生问题。该国以往关于蛇咬伤的研究主要集中在识别肇事蛇种、评估中毒的严重程度以及测试抗蛇毒血清的疗效。该国与蛇咬伤相关的因素尚未得到充分了解。这项工作的目的是确定肯尼亚已报告蛇咬伤发生率、严重程度及肇事蛇种的地区与蛇咬伤相关的药物流行病学因素。

方法

根据此前关于这些医院集水区蛇咬伤发生率、严重程度及肇事蛇种的研究结果,选择卡卡梅加省级医院、卡巴内特、卡彭古里亚和马库埃尼地区医院作为研究地点。还考虑了这些地区持续的蛇咬伤报纸报道以及肯尼亚蛇类的分布情况。对2007年至2009年期间报告的蛇咬伤病例进行回顾性审查,并收集有关发病率、年龄、咬伤部位、咬伤时间和抗蛇毒血清使用情况的数据。

结果

共记录到176例咬伤,其中91例发生在2009年。个体发病率在每年2.7/10万至6.7/10万之间。咬伤在1至15岁年龄组达到高峰,176例咬伤中有132例发生在下肢部位,49名受害者接受了抗蛇毒血清治疗。大多数咬伤发生在旱季、灌木丛中和晚上。总死亡率为2.27%。

结论

有必要提高肯尼亚公众和医护人员对蛇咬伤预防措施、急救和治疗的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7e4/6080980/23bc7d2e23c6/PAMJ-29-217-g001.jpg

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