Becker N, Lombardi P, Sidoti E, Katkin L S
Albert Einstein College of Medicine, New York, New York.
Clin Ther. 1988;10(4):401-5.
The efficacy of simethicone (available in liquid form as Mylicon Drops) in the treatment of infant colic was assessed in 51 healthy infants between 2 and 12 weeks of age. The open-label trial consisted of a one-week study period. Care-givers were to report on the infant's response to treatment after one day and one week of treatment, and in terms of the overall quality of life of both infant and family. Symptoms of colic improved or resolved in 38 infants (78%) after one day of treatment and in 44 (86%) after seven days. On both days, caregivers also noted that the quality of family life was noticeably improved. Mylicon Drops, in a dose of 0.3 ml with each feeding, can cause improvement or complete resolution of the symptoms of infant colic in the vast majority of patients and a better quality of life for both infant and family.
在51名年龄在2至12周的健康婴儿中评估了西甲硅油(以“Mylicon滴剂”的液体形式提供)治疗婴儿腹绞痛的疗效。这项开放标签试验包括为期一周的研究期。护理人员需在治疗一天和一周后报告婴儿对治疗的反应,以及婴儿和家庭的整体生活质量。治疗一天后,38名婴儿(78%)的腹绞痛症状得到改善或缓解,七天后为44名(86%)。在这两天,护理人员还指出家庭生活质量有显著改善。每次喂食服用0.3毫升的“Mylicon滴剂”,可使绝大多数患者的婴儿腹绞痛症状得到改善或完全缓解,并使婴儿和家庭的生活质量得到提高。