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用表面活性物质(西甲硅油)治疗婴儿腹绞痛。

Treatment of infantile colic with surface active substance (simethicone).

作者信息

Danielsson B, Hwang C P

出版信息

Acta Paediatr Scand. 1985 May;74(3):446-50. doi: 10.1111/j.1651-2227.1985.tb11001.x.

DOI:10.1111/j.1651-2227.1985.tb11001.x
PMID:3890465
Abstract

The effect of Simethicone on "colicky" (n = 27) infants was tested in a double-blind cross-over study. Three different parameters were used to measure the efficiency of the treatment: interviews, 24-hour records and behavioral observations. No effects of Simethicone on the symptoms of infantile colic could be demonstrated. However, 67% of the infants improved during the treatment, which could be ascribed to a high-grade placebo-effect.

摘要

在一项双盲交叉研究中测试了西甲硅油对“腹绞痛”婴儿(n = 27)的效果。使用了三个不同参数来衡量治疗效果:访谈、24小时记录和行为观察。未证明西甲硅油对婴儿腹绞痛症状有效果。然而,67%的婴儿在治疗期间症状有所改善,这可能归因于高度的安慰剂效应。

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