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琥珀酰蛋白铁复合物或葡萄糖酸铁复合物治疗缺铁性贫血的对比试验

Comparison trial of iron succinylprotein complex or iron gluconate complex in the treatment of iron deficiency anemia.

作者信息

Pedrazzoli P, Scotti A, Farina D

机构信息

Clinica Medica II, Università degli Studi de Pavia, Italy.

出版信息

Clin Ther. 1988;10(4):414-20.

PMID:3079009
Abstract

Forty patients suffering from iron deficiency anemia were randomly assigned to receive iron succinylprotein complex (containing 80 mg of elemental iron daily) or iron gluconate complex (containing 125 mg of elemental iron daily) for two months. Improvement, as measured by hematological variables, was noted in both groups, iron succinylprotein complex being superior to iron gluconate complex on some measures. Side effects were reported by two of the 20 patients treated with iron succinylprotein complex and by ten of the 20 patients treated with iron gluconate complex.

摘要

40名缺铁性贫血患者被随机分配接受琥珀酰蛋白铁复合物(每日含80毫克元素铁)或葡萄糖酸铁复合物(每日含125毫克元素铁)治疗两个月。两组患者的血液学指标均有改善,在某些指标上琥珀酰蛋白铁复合物优于葡萄糖酸铁复合物。接受琥珀酰蛋白铁复合物治疗的20名患者中有2名报告有副作用,接受葡萄糖酸铁复合物治疗的20名患者中有10名报告有副作用。

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