Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Am J Ind Med. 2019 Apr;62(4):296-308. doi: 10.1002/ajim.22963. Epub 2019 Feb 21.
This study was carried out in response to worker concerns over their exposure to lead solder and chlorinated solvents at automotive electronics manufacturing plants in Huntsville, Alabama.
A study of 4396 United Autoworkers members ever-employed at the plants between 1972 and 1993 was conducted with mortality follow-up through 2016. Poisson regression was used to estimate mortality rate ratios (RR) according to employment characteristics, including calendar period of employment.
Pre-1977 hires exhibited elevated adjusted rates of all-cause (RR, 1.29; 95% confidence interval [CI], 1.09-1.52), cardiovascular (RR, 1.38; 95% CI, 1.03-1.86), and digestive system (RR, 2.31; 95% CI, 1.04-5.10) disease mortality relative to the most recent hire group (1984-1993). Never- versus ever-employment in a skilled trade job was associated with elevated adjusted rates of all-cause, all-cancer, and cardiovascular disease mortality. Nervous system disorder mortality was greatest among 1977-1983 hires.
Elevated mortality among pre-1977 hires is consistent with worker concerns over greater exposure to hazards at the original plant building.
本研究旨在回应阿拉巴马州亨茨维尔市汽车电子制造厂工人对接触铅焊料和氯化溶剂的担忧。
对 1972 年至 1993 年间在这些工厂工作过的 4396 名美国汽车工人联合会成员进行了一项研究，并对其进行了 2016 年的死亡率随访。使用泊松回归估计了死亡率比率（RR），这些 RR 是根据就业特征，包括就业的日历时期来确定的。
1977 年以前入职的员工表现出所有原因（RR，1.29；95%置信区间[CI]，1.09-1.52）、心血管疾病（RR，1.38；95%CI，1.03-1.86）和消化系统疾病（RR，2.31；95%CI，1.04-5.10）的死亡率明显高于最近入职的员工群体（1984-1993 年）。与从事非熟练工种相比，从事技术工种的员工的所有原因、所有癌症和心血管疾病的死亡率均有所升高。1977-1983 年入职的员工神经系统疾病的死亡率最高。
1977 年以前入职的员工死亡率升高与工人对原始工厂建筑中存在更多危险的担忧一致。
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