Caglevic Christian, Anabalón Jaime, Soza Cristian, Milla Elizabeth, Gaete Fancy, Carrasco Ana María, Panay Sergio, Gallardo Carlos, Mahave Mauricio
Medical Oncology Department, Clinica Alemana Santiago; Faculty of Medicine, Universidad del Desarrollo, Santiago 456, Chile.
Oncology Institute Arturo López Pérez Foundation, Santiago 878, Chile.
Ecancermedicalscience. 2019 Jan 22;13:893. doi: 10.3332/ecancer.2019.893. eCollection 2019.
Breast cancer is the leading cause of cancer death among women worldwide. While triple-negative breast cancer is less common among various sub-types of breast cancer, it tends to affect younger women and is more aggressive, having a higher rate of early recurrence and mortality compared to other sub-types. We know about the association between triple-negative breast cancer and BRCA mutations, which are highly prevalent in founding populations of European origin, but the true prevalence of these mutations in Latin American populations is unknown. There is also very little information about the demographic and epidemiological aspects of triple-negative breast cancer in Latin America, which we will try to summarise in this article. In addition, we will try to provide a brief introduction to the most common recommendations for treating this histological class in Latin America.
乳腺癌是全球女性癌症死亡的主要原因。虽然三阴性乳腺癌在各种乳腺癌亚型中不太常见，但它往往影响年轻女性，且侵袭性更强，与其他亚型相比，早期复发率和死亡率更高。我们了解三阴性乳腺癌与BRCA突变之间的关联，BRCA突变在欧洲裔创始人群中非常普遍，但这些突变在拉丁美洲人群中的真实患病率尚不清楚。关于拉丁美洲三阴性乳腺癌的人口统计学和流行病学方面的信息也非常少，我们将在本文中对此进行总结。此外，我们还将尝试简要介绍拉丁美洲针对这种组织学类型最常见的治疗建议。
