Papadimitriou C S, Müller-Hermelink H K, Lennert K
Ann Anat Pathol (Paris). 1977;22(4):315-22.
Two cases of so-called mesenterial lymphadenitis in childhood were investigated with the immunoperoxidase technique. One more case was studied electron microscopically. All three cases were morphologically identical. In two cases infection with Yersinia enterocolitica was proven serologically. The majority of the lymphoid cells which filled the strongly distended sinuses represented electron microscopically various steps of the lymphocyte transformation. Immune histochemically, the blasts contained large amounts of immunoglobulins. It is suggested that the mitogen and adjuvant activity of bacterial lipopolysaccharides may substantially be involved in the pathogenesis of the characteristic lesion of the mesenterial lymphadenitis.
运用免疫过氧化物酶技术对两例儿童期所谓的肠系膜淋巴结炎病例进行了研究。另外对一例病例进行了电子显微镜检查。所有三例病例在形态学上是相同的。在两例病例中，血清学证实感染了小肠结肠炎耶尔森菌。充满高度扩张窦道的大多数淋巴细胞在电子显微镜下呈现出淋巴细胞转化的不同阶段。免疫组织化学显示，母细胞含有大量免疫球蛋白。有人提出，细菌脂多糖的促有丝分裂和佐剂活性可能在很大程度上参与了肠系膜淋巴结炎特征性病变的发病机制。
