Caruso R
Basic Appl Histochem. 1986;30(3):333-41.
A case of mesenteric lymphadenitis due to Yersinia pseudotuberculosis type I is described in a young adult. The diagnosis is suggested by histological appearance and confirmed by serological tests. Histological and semithin sections reveal granulomas with central microabscesses and concentric coagulative necrosis. By histochemical and immunohistochemical techniques, fibrinogen/fibrin deposits are observed as a prominent intercellular meshwork around microabscesses or as loosely intertwining strands in small granulomas. Electron microscopy shows fibrinogen/fibrin deposits closely associated both fibrous long-spacing (FLS) fibers and thin collagen fibers. The pathogenesis and type of granuloma as well as the significance of fibrinogen/fibrin deposits are discussed with reference to current literature.
本文描述了一例由I型假结核耶尔森菌引起的肠系膜淋巴结炎的年轻成人病例。诊断通过组织学表现提示，并经血清学检测证实。组织学和半薄切片显示肉芽肿伴有中央微脓肿和同心性凝固性坏死。通过组织化学和免疫组织化学技术，观察到纤维蛋白原/纤维蛋白沉积，在微脓肿周围形成突出的细胞间网络，或在小肉芽肿中呈松散交织的条索状。电子显微镜显示纤维蛋白原/纤维蛋白沉积与纤维状长间距（FLS）纤维和细胶原纤维紧密相关。参考当前文献讨论了肉芽肿的发病机制和类型以及纤维蛋白原/纤维蛋白沉积的意义。
