Maris J M, Chance B
Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia 19104.
Magn Reson Annu. 1986:213-35.
MRS made especially versatile with current technology of multinuclear coils and time interlacing of signals is appropriately suited to multifaceted tumor biochemistry, where growth is a key metabolic feature. The established results that bioenergetics and lipid metabolite concentrations show a variety of responses in tumor growth and remission in response to anticancer procedures add a further novel dimension to tumor studies by MRS. Finally, the versatility of the multinuclear MRS approach seems most appropriate to the varied nature of cancer.
随着当前多核线圈技术和信号时间交错技术的发展,磁共振波谱(MRS)变得特别通用,非常适合多方面的肿瘤生物化学研究,在肿瘤生物化学中,生长是一个关键的代谢特征。生物能量学和脂质代谢物浓度在肿瘤生长和对抗癌程序的缓解中表现出多种反应,这些已有的结果为MRS肿瘤研究增添了新的维度。最后,多核MRS方法的通用性似乎最适合癌症的多样性。