Frix A, Heinen V, Schleich F, Duysinx B, Paulus V, Louis R
Service de Pneumologie, CHU de Liège, Belgique.
Rev Med Liege. 2019 Feb;74(2):74-81.
As treating severe forms of asthma represents a medical and economical challenge, research for new therapies in this area is extensive and expansive. Recently, bronchial thermoplasty (BT) - ie. bronchoscopic procedure delivering a thermic form of energy through radiofrequency to the bronchi, in order to interfere with the components of the smooth muscle layer - arose as a promising technique. Our study followed the path of 10 patients from CHU Liège (University Hospital), who underwent this procedure in a context of severe asthma. We compared clinical and spirometric and treatment data in patients at 0 - 6 and 12 months post-procedural intervals, in order to determine whether thermoplasty had been improving asthma. Overall, we observed a stabilization and possibly a clinical improvement while reducing the total amount of exacerbation rate, and the burden of maintenance oral corticoids.
由于治疗重度哮喘是一项医学和经济挑战，该领域新疗法的研究广泛且不断扩展。最近，支气管热成形术（BT）——即通过射频向支气管传递热能形式的能量以干扰平滑肌层成分的支气管镜检查程序——作为一种有前景的技术出现了。我们的研究跟踪了来自列日大学医院（CHU Liège）的10例患者，他们在重度哮喘情况下接受了该手术。我们比较了术后0至6个月和12个月时患者的临床、肺功能和治疗数据，以确定热成形术是否改善了哮喘。总体而言，我们观察到病情稳定，甚至可能有临床改善，同时降低了总加重率以及维持口服皮质类固醇的负担。
