Roth Robert M, Rotenberg Sivan, Carmasin Jeremy, Billmeier Sarah, Batsis John A
a Department of Psychiatry , Geisel School of Medicine at Dartmouth , Lebanon , NH , USA.
b Dartmouth-Hitchcock Medical Center , Lebanon , NH , USA.
J Nutr Gerontol Geriatr. 2019 Jan-Mar;38(1):69-82. doi: 10.1080/21551197.2018.1564722. Epub 2019 Feb 22.
Bariatric surgery is the most effective approach to treating morbid obesity, resulting in decreased morbidity, mortality, and improved quality of life. Research on outcomes has generally been restricted to young and middle-aged adults, despite a growing epidemic of obesity in older adults. The use of bariatric surgery has been limited in older individuals, in part due to concerns that preexisting cognitive dysfunction increases the risk of poor post-surgical outcomes, including cognitive decline. The literature on the relationship between obesity and cognition in older adults is emerging, but fraught by several methodological limitations. While there is insufficient research to determine the nature of cognitive outcomes following bariatric surgery in older adults, the aim of this paper is to review the existing evidence and make the case for further study.
减肥手术是治疗病态肥胖最有效的方法，可降低发病率、死亡率，并改善生活质量。尽管老年人肥胖问题日益普遍，但关于手术效果的研究通常局限于中青年人群。减肥手术在老年人中的应用有限，部分原因是担心术前存在的认知功能障碍会增加术后不良后果的风险，包括认知能力下降。关于老年人肥胖与认知之间关系的文献正在不断涌现，但存在若干方法学上的局限性。虽然目前尚无足够研究来确定减肥手术对老年人认知结果的影响性质，但本文旨在综述现有证据，并为进一步研究提供依据。
