Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Cell. 2019 Feb 21;176(5):947-949. doi: 10.1016/j.cell.2019.01.053.
The adult mammalian heart is minimally regenerative after injury, whereas neonatal hearts fully recover even after major damage. New work from the Red-Horse and Woo labs (Das et al., 2019) shows that collateral artery formation is a key mechanism contributing to successful regeneration in newborn mice and provides insights into how collateral arteries form.
成年哺乳动物的心脏在受伤后几乎不能再生，而新生动物的心脏即使在遭受重大损伤后也能完全恢复。来自 Red-Horse 和 Woo 实验室的新工作（Das 等人，2019 年）表明，侧支动脉形成是促进新生小鼠成功再生的关键机制，并深入了解侧支动脉是如何形成的。
