Department of Family Medicine, School of Medicine, National Yang-Ming University, Taipei 11221, Taiwan.
Department of Family Medicine, Taipei Veterans' General Hospital, Taipei 11217, Taiwan.
Int J Environ Res Public Health. 2019 Feb 21;16(4):641. doi: 10.3390/ijerph16040641.
Anterior cervical discectomy and fusion (ACDF) is the standard surgical management for disc herniation and spondylosis worldwide and reportedly performed with short hospitalization and early discharge (ED). However, it is unknown if ED improves the outcomes of ACDF including among older adults. This cohort study included patients who underwent ACDF surgery in Taiwan over two years analyzed in two groups: the ED group (discharged within 48 hours), and the comparison group (hospitalized for more than 48 h). Both groups were followed-up for at least 180 days. Pre- and post-operative comorbidities, re-admissions and re-operations were analyzed using a multivariate cox-regression model, with bootstrapping, and Kaplan⁻Meier analysis. Among 5565 ACDF patients, the ED group ( = 405) had a higher chance (crude and adjusted hazard ratio = 2.33 and 2.39, both < 0.001) of re-admission than the comparison group ( = 5160). The ED group had an insignificant trend toward more re-admissions for spinal problems and re-operations within 180 days. In the ED group, older age (≥60) and hypertension were predictive of re-admission. For ACDF surgery, the ED group had higher rates of re-admission within 180 days of post-op, suggesting that the current approach to ED requires modification or more cautious selection criteria be adopted, particularly for older adults.
颈椎前路椎间盘切除融合术(ACDF)是目前全球治疗椎间盘突出和颈椎病的标准手术方法,该手术具有住院时间短和早期出院(ED)的特点。然而,目前尚不清楚 ED 是否会改善 ACDF 的治疗效果,包括在老年患者中的效果。这项队列研究纳入了在台湾接受 ACDF 手术的患者,在两年内分析了两组患者:ED 组(48 小时内出院)和对照组(住院时间超过 48 小时)。两组患者均至少随访 180 天。采用多变量 Cox 回归模型、 bootstrap 法和 Kaplan-Meier 分析对术前和术后合并症、再入院和再次手术进行分析。在 5565 例 ACDF 患者中,ED 组(n=405)比对照组(n=5160)更有可能再次入院(粗和调整后的危险比分别为 2.33 和 2.39,均<0.001)。ED 组在 180 天内因脊柱问题和再次手术而再次入院的趋势并不显著。在 ED 组中,年龄较大(≥60 岁)和高血压是再次入院的预测因素。对于 ACDF 手术,ED 组术后 180 天内的再入院率较高,这表明目前 ED 的方法需要修改或采用更谨慎的选择标准,尤其是在老年患者中。