Gonzalez Linda M, Wrennall Jacquie A
Psychology Service, Royal Children's Hospital, Melbourne, Australia; Brain & Mind, Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia.
Psychology Service, Royal Children's Hospital, Melbourne, Australia; Brain & Mind, Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia.
Seizure. 2020 Apr;77:29-39. doi: 10.1016/j.seizure.2018.12.013. Epub 2019 Feb 16.
This review explores the complexities of pre-surgical neuropsychological assessment for children with focal-onset epilepsy. A model is proposed outlining a range of factors that potentially influence the neuropsychological formulation. These factors include a developmental, epilepsy, psychological and cognitive dimension, together with family and social context and intrinsic factors. This model is child-centered and recognizes that these factors will be weighted differently for each individual. In some instances the neuropsychological profile might suggest localized and lateralized function, but there are significant limitations to this approach in the context of the contemporary view of epilepsy as a network disorder. This review recognizes that a range of issues impact on neuropsychological function in children with focal-onset epilepsy, including the connectivity between neural systems and the dynamic nature of development. The aim of this review is to provide a neuropsychological framework to enhance and support clinical decision-making in the pre-surgical evaluation of children with focal-onset epilepsy.
本综述探讨了局灶性癫痫发作儿童术前神经心理学评估的复杂性。提出了一个模型，概述了一系列可能影响神经心理学评估的因素。这些因素包括发育、癫痫、心理和认知维度，以及家庭和社会背景与内在因素。该模型以儿童为中心，并认识到这些因素对每个个体的权重可能不同。在某些情况下，神经心理学特征可能表明存在局部和侧化功能，但在当代将癫痫视为网络障碍的背景下，这种方法存在重大局限性。本综述认识到一系列问题会影响局灶性癫痫发作儿童的神经心理学功能，包括神经系统之间的连通性和发育的动态性质。本综述的目的是提供一个神经心理学框架，以加强和支持局灶性癫痫发作儿童术前评估中的临床决策。
