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衰老、代谢性酸中毒和肾衰竭:相互加速的过程。

Aging, metabolic acidosis and renal failure: Interactive accelerating processes.

机构信息

University of California San Francisco, San Francisco CA, United States.

University of California San Francisco, San Francisco CA, United States.

出版信息

Med Hypotheses. 2019 Mar;124:95-97. doi: 10.1016/j.mehy.2019.02.015. Epub 2019 Feb 4.

Abstract

In this article, we hypothesize that eating a low acid (and particularly a low phosphate) diet and/or supplementing the diet with base precursors such as bicarbonate would have a number of helpful effects on aging, by:Although the present data is mainly from studies in invertebrate and small animal models, extrapolation of these results, as well as some associated results in human studies, suggests that low acid diets, or neutralization of the low grade metabolic acidosis seen in aging human subjects would possibly allow us to live longer and remain healthier.

摘要

在本文中,我们假设食用低酸(特别是低磷酸盐)饮食和/或用碳酸氢盐等碱前体补充饮食,可能会通过以下方式对衰老产生多种有益影响:尽管目前的数据主要来自无脊椎动物和小动物模型的研究,但这些结果的推断以及人类研究中的一些相关结果表明,低酸饮食,或中和衰老人体中观察到的轻度代谢性酸中毒,可能使我们活得更长、更健康。

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