Stockley R A, Burnett D, Bradwell A R
Clin Chim Acta. 1978 Aug 15;88(1):127-33. doi: 10.1016/0009-8981(78)90159-6.
The effect of passage through the lung on alpha1-antitrypsin was studied in sixteen patients with chronic obstructive airways disease. The average mixed venous value of alpha1-antitrypsin (106.2% standard serum value) was not different from the the mean arterial value (105.6%). Where individual differences were found there was a similar difference in serum albumin. However, there was a small but significant rise (p less than 0.005) in serum alpha1-antitrypsin "complex" as blood traversed the lung (mixed value = 6.3%; mixed arterial value = 6.8%). The reason is not yet clear.
对16例慢性阻塞性气道疾病患者研究了α1-抗胰蛋白酶经肺循环后的变化。α1-抗胰蛋白酶的平均混合静脉值（为标准血清值的106.2%）与平均动脉值（105.6%）无差异。在发现个体差异的情况下，血清白蛋白也有类似差异。然而，当血液流经肺时，血清α1-抗胰蛋白酶“复合物”有小幅但显著的升高（p<0.005）（混合值=6.3%；混合动脉值=6.8%）。原因尚不清楚。
