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妊娠急性脂肪肝与计算机断层扫描诊断

Acute fatty liver of pregnancy and diagnosis by computed tomography.

作者信息

McKee C M, Weir P E, Foster J H, Murnaghan G A, Callender M E

出版信息

Br Med J (Clin Res Ed). 1986 Feb 1;292(6516):291-2. doi: 10.1136/bmj.292.6516.291.

DOI:10.1136/bmj.292.6516.291
PMID:3080142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1339273/
Abstract

A 39 year old woman was admitted to a maternity unit at 34 weeks' gestation with nausea, vomiting, and jaundice. Her condition deteriorated, and she was transferred to hospital, deeply unconscious and hypotensive. The diagnosis of acute fatty liver of pregnancy was initially suggested by the typical history of prodromal malaise and vomiting and the rapid onset of hepatic encephalopathy with profound hypoglycaemia and only small increases in transaminase activities. Computed tomography was performed: there was no enlargement of the liver or spleen, but the attenuation value over the liver indicated appreciable fatty infiltration of the liver, establishing the diagnosis of acute fatty liver of pregnancy. Computed tomography is of value in the diagnosis of liver disease of late pregnancy, and this technique may become the method of choice for the investigation of acute fatty liver of pregnancy.

摘要

一名39岁女性在妊娠34周时因恶心、呕吐和黄疸入住产科病房。她的病情恶化,被转至医院,深度昏迷且血压过低。妊娠急性脂肪肝的诊断最初是由前驱不适和呕吐的典型病史、伴有严重低血糖的肝性脑病迅速发作以及转氨酶活性仅小幅升高所提示的。进行了计算机断层扫描:肝脏和脾脏没有肿大,但肝脏的衰减值表明肝脏有明显的脂肪浸润,从而确诊为妊娠急性脂肪肝。计算机断层扫描在妊娠晚期肝病的诊断中具有价值,该技术可能会成为妊娠急性脂肪肝检查的首选方法。

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Acute fatty liver of pregnancy and diagnosis by computed tomography.妊娠急性脂肪肝与计算机断层扫描诊断
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The diagnosis of acute fatty liver of pregnancy by computed tomography.通过计算机断层扫描诊断妊娠急性脂肪肝。
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引用本文的文献

1
Idiopathic acute fatty liver of pregnancy: three cases including a subsequent normal pregnancy.妊娠特发性急性脂肪肝:三例报告,其中一例后续妊娠正常。
Ulster Med J. 1990 Oct;59(2):217-20.

本文引用的文献

1
Idiopathic acute fatty liver of pregnancy in 12 patients.12例妊娠特发性急性脂肪肝。
Q J Med. 1982;51(204):481-97.
2
Acute fatty liver of pregnancy and the microvesicular fat diseases.妊娠期急性脂肪肝与微泡性脂肪性疾病
Gut. 1983 Apr;24(4):265-9. doi: 10.1136/gut.24.4.265.
3
Idiopathic acute fatty liver of pregnancy. Death from extrahepatic manifestations.妊娠特发性急性脂肪肝。死于肝外表现。
Am J Dig Dis. 1972 Feb;17(2):167-78. doi: 10.1007/BF02232739.