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烧伤创伤患者的颈椎损伤:发病率、预测因素及预后

Cervical Spine Injury in Burned Trauma Patients: Incidence, Predictors, and Outcomes.

作者信息

Galganski Laura A, Cox Jessica A, Greenhalgh David G, Sen Soman, Romanowski Kathleen S, Palmieri Tina L

机构信息

Department of Surgery, Division of Burn Surgery, University of California, Davis, California.

Shriners Hospital for Children - Northern California, Sacramento, California.

出版信息

J Burn Care Res. 2019 Apr 26;40(3):263-268. doi: 10.1093/jbcr/irz022.

Abstract

Cervical spine injuries (CIs) carry significant morbidity and mortality; hence, cervical spine immobilization is used liberally in trauma patients, including burns. The incidence, predictors, and outcomes of CI in burn patients are unknown. A retrospective cohort from the National Trauma Data Bank between 2007 and 2012 included all burned patients with and without CI. Predictors of CI were identified by logistic regression. Outcomes with and without CI were compared with Wilcoxon rank sum test. A total of 94,964 patients were identified with burn injuries. The incidence of CI was 0.79% (n = 745). Mechanism of injury, age, and injury severity score (ISS) were significant predictors of CI. Odds of CI were 109.4 (95% CI: 61.2-195.3, P < .0001) for motor vehicle injury, 87.8 (95% CI: 47.0-164.0, P < .0001) for falls, 1.2 (95% CI: 0.6-2.3, P = .66) for fire/flame, and 2.4 (95% CI: 1.0-5.5, P < .0001) for explosion compared with reference of hot object/substance. For every year increase in age, there were 1.02 higher odds of CI (95% CI: 1.01-1.02, P < .0001). For each point increase in ISS, there were 1.05 higher odds of CI (95% CI: 1.04-1.05, P < .0001). Patients with CI had higher mortality (10.3% vs 2.9%, P < .0001), longer total length of stay (12.0 vs 2.0 days, P < .0001), intensive care unit length of stay (4.0 vs 0.0 days, P < .001), and ventilator days (1.0 vs 0.0 days, P < .0001). The incidence of CI in burn patients is low, especially when due to fire, flame, or scalds; however, CI is associated with higher mortality and worse outcomes.

摘要

颈椎损伤(CIs)具有较高的发病率和死亡率;因此,颈椎制动在创伤患者(包括烧伤患者)中被广泛应用。烧伤患者中颈椎损伤的发生率、预测因素和预后尚不清楚。一项对2007年至2012年国家创伤数据库的回顾性队列研究纳入了所有有或无颈椎损伤的烧伤患者。通过逻辑回归确定颈椎损伤的预测因素。采用Wilcoxon秩和检验比较有无颈椎损伤患者的预后。共识别出94964例烧伤患者。颈椎损伤的发生率为0.79%(n = 745)。损伤机制、年龄和损伤严重程度评分(ISS)是颈椎损伤的重要预测因素。与热物体/物质烧伤相比,机动车损伤导致颈椎损伤的几率为109.4(95%置信区间:61.2 - 195.3,P <.0001),跌倒为87.8(95%置信区间:47.0 - 164.0,P <.0001),火灾/火焰为1.2(95%置信区间:0.6 - 2.3,P =.66),爆炸为2.4(95%置信区间:1.0 - 5.5,P <.0001)。年龄每增加一岁,颈椎损伤的几率增加1.02(95%置信区间:1.01 - 1.02,P <.0001)。ISS每增加一分,颈椎损伤的几率增加1.05(95%置信区间:1.04 - 1.05,P <.0001)。有颈椎损伤的患者死亡率更高(10.3%对2.9%,P <.0001),总住院时间更长(12.0天对2.0天,P <.0001),重症监护病房住院时间更长(4.0天对0.0天,P <.001),机械通气天数更多(1.0天对0.0天,P <.0001)。烧伤患者中颈椎损伤的发生率较低,尤其是因火灾、火焰或烫伤导致的;然而,颈椎损伤与更高的死亡率和更差的预后相关。

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