Fang M A, Reinig J W, Hill S C, Marini J, Zasloff M A
Clin Nucl Med. 1986 Jan;11(1):8-9. doi: 10.1097/00003072-198601000-00003.
The extensive heterotopic bone formation in patients with fibrodysplasia ossificans progressiva (FOP) has been documented previously with radiographs. A case in which a Tc-99m MDP bone scan showed increased uptake at sites well before ossification could be documented radiographically is described. This finding suggests that bone scans would likely be useful to monitor the extent of involvement with FOP and to detect areas of new activity.
进行性骨化性纤维发育不良(FOP)患者广泛的异位骨形成此前已通过X线片得到记录。本文描述了一例病例,其中锝-99m亚甲基二膦酸盐(Tc-99m MDP)骨扫描显示,在X线片能够记录到骨化之前,某些部位就出现了摄取增加。这一发现表明,骨扫描可能有助于监测FOP的受累范围,并检测新的活动区域。