From the Department of Nuclear Medicine and PET/CT Mahajan Imaging Centre, Sir Ganga Ram Hospital, New Delhi, India.
Clin Nucl Med. 2020 Sep;45(9):694-695. doi: 10.1097/RLU.0000000000003186.
Fibrodysplasia ossificans progressiva is a rare debilitating, connective tissue disease characterized by progressive extraosseous ossification with abnormal great toes. Clinical (hallux valgus), radiological, and classical bone scan findings help to reach diagnosis and prevent patient from unnecessary surgical interventions for fibrodysplasia ossificans progressiva lesions and radiotherapy cycles. Here we present a case where a child presented with multiple swellings over the body and hallux valgus, and further bone scan findings helped to reach the diagnosis. The progressive nature of disease is difficult to halt, but early diagnosis can help in the delay of the disease process, by preventing trauma and giving disease-modifying agents.
进行性骨化性纤维发育不良是一种罕见的使人虚弱的结缔组织疾病，其特征是进行性骨外骨化和异常的大脚趾。临床（踇外翻）、放射学和经典骨扫描结果有助于做出诊断，并防止患者因进行性骨化性纤维发育不良病变和放射治疗周期而进行不必要的手术干预。在这里，我们介绍了一个孩子，他的身体多处肿胀和踇外翻，进一步的骨扫描结果有助于做出诊断。疾病的进行性难以阻止，但早期诊断可以通过预防创伤和使用疾病修饰剂来帮助延缓疾病进程。
