Guillen-Romero Luis Daniel, Oropeza-Guzmán Mercedes Teresita, López-Maldonado Eduardo Alberto, Iglesias Ana Leticia, Paz-González Juan Antonio, Ng Theodore, Serena-Gómez Eduardo, Villarreal-Gómez Luis Jesús
1 Escuela de Ciencias de la Ingeniería y Tecnología, Universidad Autónoma de Baja California, Unidad Valle de las Palmas, Tijuana, Baja California, México.
2 Centro de Graduados, Instituto Tecnológico de Tijuana, Tijuana, Baja California, México.
J Appl Biomater Funct Mater. 2019 Jan-Mar;17(1):2280800018817463. doi: 10.1177/2280800018817463.
An approach to solve the limitations of autologous bone grafting procedures in bone injury treatment is to develop bioactive coatings in the implantation system. The objective of this work is to compare the temperature effect on the stability of hydroxyapatite, graphene, and collagen colloidal suspensions to be used as biocompatible and bioactive coatings on a carbon fiber composite surface. Synthesized hydroxyapatite was assessed by X-ray diffraction. Zeta potential at different temperatures was evaluated. Specimens were characterized using scanning electron microscopy and Raman analysis. The results showed that the best hydroxyapatite/graphene ratio was 85/15, while those of the hydroxyapatite/collagen mixtures were 85/15. A hydroxyapatite/graphene/collagen mixture was synthesized based on these results.
解决自体骨移植手术在骨损伤治疗中局限性的一种方法是在植入系统中开发生物活性涂层。这项工作的目的是比较温度对羟基磷灰石、石墨烯和胶原胶体悬浮液稳定性的影响，这些悬浮液将用作碳纤维复合材料表面的生物相容性和生物活性涂层。通过X射线衍射对合成的羟基磷灰石进行评估。评估了不同温度下的zeta电位。使用扫描电子显微镜和拉曼分析对样品进行表征。结果表明，最佳的羟基磷灰石/石墨烯比例为85/15，而羟基磷灰石/胶原混合物的比例为85/15。基于这些结果合成了羟基磷灰石/石墨烯/胶原混合物。
