Yang Muyue, Yang Zhen, Yuan Tifei, Feng Wuwei, Wang Pu
Department of Rehabilitation Medicine, Ruijin Hospital, Shanghai, China.
School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Front Neurol. 2019 Feb 5;10:58. doi: 10.3389/fneur.2019.00058. eCollection 2019.
Survivors of stroke often experience significant disability and impaired quality of life. The recovery of motor or cognitive function requires long periods. Neuroimaging could measure changes in the brain and monitor recovery process in order to offer timely treatment and assess the effects of therapy. A non-invasive neuroimaging technique near-infrared spectroscopy (NIRS) with its ambulatory, portable, low-cost nature without fixation of subjects has attracted extensive attention. We conducted a comprehensive literature review in order to review the use of NIRS in stroke or post-stroke patients in July 2018. NCBI Pubmed database, EMBASE database, Cochrane Library and ScienceDirect database were searched. Overall, we reviewed 66 papers. NIRS has a wide range of application, including in monitoring upper limb, lower limb recovery, motor learning, cortical function recovery, cerebral hemodynamic changes, cerebral oxygenation, as well as in therapeutic method, clinical researches, and evaluation of the risk for stroke. This study provides a preliminary evidence of the application of NIRS in stroke patients as a monitoring, therapeutic, and research tool. Further studies could give more emphasize on the combination of NIRS with other techniques and its utility in the prevention of stroke.
中风幸存者常常经历严重的残疾和生活质量受损。运动或认知功能的恢复需要很长时间。神经成像可以测量大脑的变化并监测恢复过程，以便提供及时的治疗并评估治疗效果。一种非侵入性神经成像技术——近红外光谱（NIRS），因其具有可移动、便携、低成本且无需受试者固定的特点而备受关注。2018年7月，我们进行了一项全面的文献综述，以回顾NIRS在中风或中风后患者中的应用情况。我们检索了NCBI Pubmed数据库、EMBASE数据库、Cochrane图书馆和ScienceDirect数据库。总体而言，我们回顾了66篇论文。NIRS有广泛的应用，包括监测上肢、下肢恢复、运动学习、皮质功能恢复、脑血流动力学变化、脑氧合，以及在治疗方法、临床研究和中风风险评估方面。本研究为NIRS作为中风患者的监测、治疗和研究工具的应用提供了初步证据。进一步的研究可以更加强调NIRS与其他技术的结合及其在预防中风方面的效用。
