Utkina Natalia K, Denisenko Vladimir A
Nat Prod Commun. 2016 Sep;11(9):1259-1260.
A new compound, N-demethylaaptanone (5), having an oxygenated 1,6-naphthyridine core, has been isolated from the Vietnamese marine sponge Aaptos aaptos, along with the known metabolites, aaptamine (1), isoaaptamine (2), 9-demethylaaptamine (3), and aaptanone (4). The structure of N-demethylaaptanone was determined as 9-hydroxy-8-methoxy-4H-benzo[de][1,6]-naphthyridine-5,6-dione from spectroscopic data.
一种具有氧化的1,6-萘啶核心的新化合物N-去甲基aaptanone（5）已从越南海洋海绵Aaptos aaptos中分离出来，同时还分离出了已知的代谢产物aaptamine（1）、异aaptamine（2）、9-去甲基aaptamine（3）和aaptanone（4）。根据光谱数据，N-去甲基aaptanone的结构被确定为9-羟基-8-甲氧基-4H-苯并[de][1,6]-萘啶-5,6-二酮。
