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在英国家庭护理机构中患有痴呆症的人群中,激越的医疗资源利用情况和费用——管理激越和提高痴呆症生活质量(MARQUE)研究。

Healthcare resource utilisation and costs of agitation in people with dementia living in care homes in England - The Managing Agitation and Raising QUality of LifE in Dementia (MARQUE) study.

机构信息

Research Department of Primary Care & Population Health and Priment Clinical Trials Unit, Institute of Epidemiology & Health Care, University College London, London, United Kingdom.

Department of Old Age Psychiatry, Division of Psychiatry, University College London, London, United Kingdom.

出版信息

PLoS One. 2019 Feb 26;14(2):e0211953. doi: 10.1371/journal.pone.0211953. eCollection 2019.

Abstract

BACKGROUND

People with dementia living in care homes often experience clinically significant agitation; however, little is known about its economic impact.

OBJECTIVE

To calculate the cost of agitation in people with dementia living in care homes.

METHODS

We used the baseline data from 1,424 residents with dementia living in care homes (part of Managing Agitation and Raising QUality of lifE in dementia (MARQUE) study) that had Cohen-Mansfield Agitation Inventory (CMAI) scores recorded. We investigated the relationship between residents' health and social care costs and severity of agitation based on the CMAI total score. In addition, we assessed resource utilisation and compared costs of residents with and without clinically significant symptoms of agitation using the CMAI over and above the cost of the care home.

RESULTS

Agitation defined by the CMAI was a significant predictor of costs. On average, a one-point increase in the CMAI will lead to a 0.5 percentage points (cost ratio 1.005, 95%CI 1.001 to 1.010) increase in the annual costs. The excess annual cost associated with agitation per resident with dementia was £1,125.35. This suggests that, on average, agitation accounts for 44% of the annual health and social care costs of dementia in people living in care homes.

CONCLUSION

Agitation in people with dementia living in care homes contributes significantly to the overall costs increasing as the level of agitation increases. Residents with the highest level of agitation cost nearly twice as much as those with the lowest levels of agitation, suggesting that effective strategies to reduce agitation are likely to be cost-effective in this setting.

摘要

背景

居住在养老院的痴呆症患者常经历具有临床意义的激越;然而,其经济影响知之甚少。

目的

计算居住在养老院的痴呆症患者激越的成本。

方法

我们使用了 1424 名居住在养老院的痴呆症患者(管理激越和提高痴呆症生活质量(MARQUE)研究的一部分)的基线数据,这些患者的 Cohen-Mansfield 激越量表(CMAI)评分已记录。我们根据 CMAI 总分研究了居民的健康和社会保健成本与激越严重程度之间的关系。此外,我们评估了资源利用情况,并使用 CMAI 评估了有和无临床显著激越症状的居民的成本,超过了养老院的费用。

结果

CMAI 定义的激越是成本的一个显著预测因子。平均而言,CMAI 增加一个点将导致年度成本增加 0.5 个百分点(成本比 1.005,95%CI 1.001 至 1.010)。每位痴呆症患者因激越导致的年额外成本为 1125.35 英镑。这表明,平均而言,激越占养老院居住的痴呆症患者年度健康和社会保健成本的 44%。

结论

居住在养老院的痴呆症患者的激越与总体成本增加密切相关,随着激越程度的增加而增加。激越程度最高的居民的成本几乎是激越程度最低的居民的两倍,这表明在这种情况下,减少激越的有效策略可能具有成本效益。

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