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垂体腺瘤放疗30年后双侧外耳道放射性诱导鳞状细胞癌:一例报告

Bilateral radiation-induced squamous cell carcinomas of the external auditory canal 30 years after radiotherapy for a pituitary adenoma: a case report.

作者信息

De Roeck Laurien, Nuyts Sandra

机构信息

Department of Radiation Oncology, University Hospitals Leuven, Belgium.

Department of Oncology, Experimental Radiotherapy, KU Leuven-University of Leuven, Belgium.

出版信息

Tumori. 2019 Dec;105(6):NP4-NP7. doi: 10.1177/0300891619832258. Epub 2019 Feb 26.

Abstract

INTRODUCTION

The most important long-term effect of radiotherapy is induction of secondary cancers. A rare radiation-induced tumor is a squamous cell carcinoma of the external auditory canal. Case reports have been described in Asian patients after radiotherapy for nasopharyngeal cancer.

CASE DESCRIPTION

We describe an unusual case report of a 53-year-old Caucasian man who developed squamous cell carcinomas of the right and left external auditory canal, respectively 29 and 30 years after radiotherapy for a pituitary adenoma.

CONCLUSION

In young patients with benign tumors, we should always evaluate whether the benefits of radiotherapy outweigh the risks and side effects. After radiotherapy, screening programs should be developed since early detection improves salvage treatment of these secondary and often morbid tumors.

摘要

引言

放射治疗最重要的长期影响是诱发继发性癌症。一种罕见的辐射诱发肿瘤是外耳道鳞状细胞癌。已有亚洲患者在鼻咽癌放疗后出现此类病例报告。

病例描述

我们报告一例不寻常的病例,一名53岁的白种男性,在垂体腺瘤放疗后分别于29年和30年时发生了右侧和左侧外耳道鳞状细胞癌。

结论

对于患有良性肿瘤的年轻患者,我们应始终评估放疗的益处是否超过风险和副作用。放疗后应制定筛查计划,因为早期发现可改善这些继发性且往往病情严重的肿瘤的挽救治疗。

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