Department of Radiology, Nihon University School of Medicine, Tokyo, Japan.
Department of Otolaryngology-Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan.
Head Neck. 2019 Jul;41(7):E113-E119. doi: 10.1002/hed.25728. Epub 2019 Mar 4.
Radiation-induced bilateral external auditory canal cancer is an extremely rare disease that has yet to be fully characterized in the clinical literature.
Herein, we present a case study of a 75-year-old man with radiation-induced bilateral external auditory canal cancer. The patient's medical history included left maxillary cancer that had been treated with chemoradiation 19 years earlier and local recurrence with total maxillectomy 10 years earlier. Intracavitary radiation was delivered to the site of postoperative recurrence 8 years before the current presentation. The patient declined radical surgery for the external auditory canal cancer at this time, and a customized combined modality regimen was thus administered.
There was no recurrence of cancer for 22 months, to date, after completing chemoradiotherapy.
Our finding that radiotherapy can be successfully used for radiation-induced cancer indicates that chemoradiotherapy may be a useful strategy for treating this type of malignancy.
放射诱导的双侧外耳道癌是一种极为罕见的疾病，在临床文献中尚未得到充分描述。
本研究报告了一例 75 岁男性放射诱导的双侧外耳道癌病例。该患者的病史包括 19 年前接受过放化疗的左侧上颌癌和 10 年前因局部复发而进行的全上颌骨切除术。在本次就诊前 8 年，曾对术后复发部位进行了腔内放射治疗。当时，患者拒绝了根治性手术，因此采用了定制的联合治疗方案。
在完成放化疗后 22 个月，癌症至今无复发。
我们发现放射治疗可成功用于治疗放射诱导的癌症，这表明放化疗可能是治疗这种恶性肿瘤的一种有效策略。
