• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Polygenic Risk Scores That Predict Common Diseases Using Millions of Single Nucleotide Polymorphisms: Is More, Better?

作者信息

Janssens A Cecile JW, Joyner Michael J

机构信息

Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta GA;

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN.

出版信息

Clin Chem. 2019 May;65(5):609-611. doi: 10.1373/clinchem.2018.296103. Epub 2019 Feb 26.

DOI:10.1373/clinchem.2018.296103
PMID:30808642
Abstract
摘要

相似文献

1
Polygenic Risk Scores That Predict Common Diseases Using Millions of Single Nucleotide Polymorphisms: Is More, Better?利用数百万个单核苷酸多态性预测常见疾病的多基因风险评分：更多就更好吗？
Clin Chem. 2019 May;65(5):609-611. doi: 10.1373/clinchem.2018.296103. Epub 2019 Feb 26.
2
Polygenic risk scores and the prediction of common diseases.多基因风险评分与常见疾病的预测
Int J Epidemiol. 2020 Feb 1;49(1):1-3. doi: 10.1093/ije/dyz254.
3
Polygenic scores: Are they a public health hazard?多基因风险评分：它们是公共健康危害吗？
Prog Biophys Mol Biol. 2019 Dec;149:4-8. doi: 10.1016/j.pbiomolbio.2019.08.004. Epub 2019 Aug 6.
4
Attention-deficit/hyperactivity disorder polygenic risk scores predict attention problems in a population-based sample of children.注意缺陷多动障碍多基因风险评分可预测基于人群的儿童注意力问题。
J Am Acad Child Adolesc Psychiatry. 2014 Oct;53(10):1123-9.e6. doi: 10.1016/j.jaac.2014.06.014. Epub 2014 Aug 19.
5
[From genome-wide association studies (gwas) to genome-wide polygenic scores (GPS)].[从全基因组关联研究（GWAS）到全基因组多基因评分（GPS）]
Med Sci (Paris). 2018 Dec;34(12):1116-1122. doi: 10.1051/medsci/2018290. Epub 2019 Jan 9.
6
Polygenic risk scores: a biased prediction?多基因风险评分：有偏差的预测？
Genome Med. 2018 Dec 27;10(1):100. doi: 10.1186/s13073-018-0610-x.
7
[Common and rare variants, polygenic traits and missing heritability].[常见和罕见变异、多基因性状与缺失的遗传力]
Med Sci (Paris). 2017 Jun-Jul;33(6-7):674-676. doi: 10.1051/medsci/20173306028. Epub 2017 Jul 19.
8
Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits.使用来自 32 种复杂性状的全基因组关联研究的汇总水平统计数据估计复杂效应大小分布。
Nat Genet. 2018 Sep;50(9):1318-1326. doi: 10.1038/s41588-018-0193-x. Epub 2018 Aug 13.
9
[Polygenic risk prediction of common diseases: from epidemiology to clinical application].[常见疾病的多基因风险预测：从流行病学到临床应用]
Ned Tijdschr Geneeskd. 2019 Sep 24;163:D3870.
10
Polygenic link between blood lipids and amyotrophic lateral sclerosis.血脂与肌萎缩侧索硬化症的多基因关联。
Neurobiol Aging. 2018 Jul;67:202.e1-202.e6. doi: 10.1016/j.neurobiolaging.2018.03.022. Epub 2018 Mar 27.

引用本文的文献

1
Exploring the genetics of airflow limitation in lung function across the lifespan - a polygenic risk score study.探索一生中肺功能气流受限的遗传学——一项多基因风险评分研究。
EClinicalMedicine. 2024 Aug 12;75:102731. doi: 10.1016/j.eclinm.2024.102731. eCollection 2024 Sep.
2
Lifestyle predictors of colorectal cancer in European populations: a systematic review.欧洲人群中结直肠癌的生活方式预测因素：一项系统综述
BMJ Nutr Prev Health. 2024 Jan 4;7(1):183-190. doi: 10.1136/bmjnph-2022-000554. eCollection 2024.
3
A Polygenic Risk Analysis for Identifying Ulcerative Colitis Patients with European Ancestry.
用于识别欧洲血统溃疡性结肠炎患者的多基因风险分析。
Genes (Basel). 2024 May 25;15(6):684. doi: 10.3390/genes15060684.
4
Evaluating the Classification Accuracy of Expression Quantitative Trait Loci Calculated Polygenic Risk Scores in Alzheimer's Disease.评估阿尔茨海默病中基于表达数量性状基因座计算的多基因风险评分的分类准确性。
Int J Mol Sci. 2023 Aug 14;24(16):12799. doi: 10.3390/ijms241612799.
5
Polygenic risk scores in pharmacogenomics: opportunities and challenges-a mini review.药物基因组学中的多基因风险评分：机遇与挑战——一篇小型综述
Front Genet. 2023 Jun 15;14:1217049. doi: 10.3389/fgene.2023.1217049. eCollection 2023.
6
Polygenic Risk Score in African populations: progress and challenges.非洲人群中的多基因风险评分：进展与挑战。
F1000Res. 2023 Apr 11;11:175. doi: 10.12688/f1000research.76218.2. eCollection 2022.
7
Modifiable cardiovascular risk factors and genetics for targeted prevention of dementia.可改变的心血管危险因素和遗传学在痴呆症的靶向预防中的作用。
Eur Heart J. 2023 Jul 21;44(28):2526-2543. doi: 10.1093/eurheartj/ehad293.
8
How do experts in psychiatric genetics view the clinical utility of polygenic risk scores for schizophrenia?精神遗传学专家如何看待精神分裂症多基因风险评分的临床实用性？
Am J Med Genet B Neuropsychiatr Genet. 2023 Oct-Dec;192(7-8):161-170. doi: 10.1002/ajmg.b.32939. Epub 2023 May 9.
9
The necessity of incorporating non-genetic risk factors into polygenic risk score models.将非遗传风险因素纳入多基因风险评分模型的必要性。
Sci Rep. 2023 Feb 20;13(1):1351. doi: 10.1038/s41598-023-27637-w.
10
Learning high-order interactions for polygenic risk prediction.学习多基因风险预测的高阶交互作用。
PLoS One. 2023 Feb 10;18(2):e0281618. doi: 10.1371/journal.pone.0281618. eCollection 2023.