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玻璃体切除联合内界膜瓣技术治疗视盘小凹相关黄斑裂孔性视网膜脱离的疗效。

Efficacy of Internal Limiting Membrane Flap Techniques with Vitrectomy for Macular Detachment Associated with an Optic Disc Pit.

机构信息

Vall d'Hebron University Hospital, Barcelona, Spain.

Ophthalmology Research, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.

出版信息

Ophthalmologica. 2019;242(1):38-48. doi: 10.1159/000495621. Epub 2019 Mar 22.

Abstract

PURPOSE

To compare the anatomical and functional outcome of adjuvant pars plana vitrectomy (PPV) procedures using the techniques of translocation of an internal limiting membrane (ILM) flap and transplantation of an inverted ILM flap for the treatment of chronic and/or refractory optic disc pit (ODP) maculopathy.

METHODS

In this prospective interventional case series study, 9 patients (9 eyes) with chronic and/or refractory ODP maculopathy underwent PPV with either translocation of an ILM flap or transplantation of an inverted ILM flap as adjuvant techniques along with gas tamponade. The anatomical success, rates of macular reattachment, and visual improvement were assessed.

RESULTS

The mean preoperative central retinal thickness (CRT) was 723.4 µm (range: 366-1,151). The mean postoperative CRT was 398.1 ± 212.2 µm (range: 210-758). An increased preoperative CRT was associated with a lower chance of postoperative reattachment of the macula (p = 0.047). The overall reattachment rate at the end of the follow-up period was 56% (n = 5). The mean preoperative visual acuity (logMAR unit [Snellen acuity]) was 0.48 (20/60) (range: 1.30 [20/400] to 0.10 [20/25]). The mean change in best corrected visual acuity (BCVA) was 0.48 ± 0.233 logMAR units (approx. 3 lines of visual improvement).

CONCLUSIONS

ILM flap techniques are logical and straightforward approaches as adjuvants to PPV treatment of ODP maculopathy. They could be viable adjuvant treatments for improvement in BCVA and CRT in patients with ODP maculopathy.

摘要

目的

比较内界膜(ILM)瓣移位和 ILM 瓣翻转移植辅助平面内玻璃体切除术(PPV)治疗慢性和/或难治性视盘小凹(ODP)黄斑病变的解剖和功能结果。

方法

在这项前瞻性干预性病例系列研究中,9 名(9 只眼)慢性和/或难治性 ODP 黄斑病变患者接受了 PPV 治疗,同时采用 ILM 瓣移位或 ILM 瓣翻转移植作为辅助技术,并进行了气体填充。评估了解剖成功率、黄斑再附着率和视力改善情况。

结果

平均术前中心视网膜厚度(CRT)为 723.4 µm(范围:366-1151 µm)。平均术后 CRT 为 398.1 ± 212.2 µm(范围:210-758 µm)。术前 CRT 增加与术后黄斑再附着的机会降低相关(p = 0.047)。随访期末总再附着率为 56%(n = 5)。平均术前视力(logMAR 单位[Snellen 视力])为 0.48(20/60)(范围:1.30 [20/400]至 0.10 [20/25])。最佳矫正视力(BCVA)的平均变化为 0.48 ± 0.233 logMAR 单位(约 3 行视力改善)。

结论

ILM 瓣技术作为 PPV 治疗 ODP 黄斑病变的辅助手段是合理且直接的方法。对于 ODP 黄斑病变患者,它们可能是改善 BCVA 和 CRT 的可行辅助治疗方法。

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