Pastor-Idoate Salvador, García-Arumí Fusté Claudia, García-Onrubia Luis, Copete Sergio, García-Arumí José
IOBA Eye Institute, University of Valladolid, Valladolid, Spain.
Clinical University Hospital of Valladolid, Valladolid, Spain.
Clin Ophthalmol. 2020 Jun 16;14:1601-1608. doi: 10.2147/OPTH.S250921. eCollection 2020.
Optic disc pit (ODP) is a rare congenital optic nerve head abnormality, which can be complicated by intraretinal and subretinal fluid at the macula (ODP-maculopathy) with progressive visual loss. The source of this fluid remains unclear and the most dominant hypotheses have pointed to vitreous cavity or cerebrospinal fluid. Although spontaneous resolution has been reported, the majority of untreated cases of ODP-maculopathy result in final visual acuity less than 20/200 or worse. A wide array of interventions, either individually or in combination with adjuvant treatments, have been tried with varying degrees of success. Recently, different surgical procedures to fill the ODP by self-sealing materials in combination with pars plana vitrectomy have been reported as an effective adjuvant treatment. However, given the relative rarity of this condition, the majority of reports describe a small retrospective case series, making it difficult to compare among different treatments options and create a consensus regarding the optimal treatment for ODP-maculopathy. In this situation, a mini-review about surgical treatment modalities and their results can be a useful approach to identify the most effective surgical option in the management of ODP-maculopathy.
视盘小凹（ODP）是一种罕见的先天性视神经乳头异常，可伴有黄斑区视网膜内和视网膜下液体积聚（ODP-黄斑病变），导致视力进行性下降。这种液体的来源尚不清楚，最主要的假说是指向玻璃体腔或脑脊液。虽然有自发缓解的报道，但大多数未经治疗的ODP-黄斑病变病例最终视力会低于20/200或更差。人们尝试了各种各样的干预措施，单独或与辅助治疗联合使用，取得了不同程度的成功。最近，有报道称采用自封闭材料填充ODP并联合玻璃体切割术的不同手术方法是一种有效的辅助治疗。然而，鉴于这种情况相对罕见，大多数报告描述的是小样本回顾性病例系列，这使得难以比较不同的治疗选择并就ODP-黄斑病变的最佳治疗达成共识。在这种情况下，对手术治疗方式及其结果进行小型综述可能是确定ODP-黄斑病变管理中最有效手术选择的有用方法。
