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异丙酚致难治性癫痫持续状态患者出现绿色尿液

Propofol-Induced Green Urine in a Patient with Refractory Status Epilepticus.

作者信息

Lee Da Eun, Chung Kyuyoon, Cho Joong-Yang, Lee Jae Jung, Park Hea Ree, Song Pamela

机构信息

Department of Nursing, Ilsan Paik Hospital, Inje University, Goyang, Korea.

Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.

出版信息

J Epilepsy Res. 2018 Dec 31;8(2):97-99. doi: 10.14581/jer.18017. eCollection 2018 Dec.

DOI:10.14581/jer.18017
PMID:30809505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6374538/
Abstract

Propofol is commonly used for induction and maintenance of anesthesia, and sedation in the intensive care unit. In addition, it is also used as an anesthetic coma treatment for refractory status epilepticus. We present the case of a 52-year-old man, who developed green urine following propofol coma therapy for status epilepticus. The urine color recovered following discontinuation of propofol infusion. The green discoloration of urine is a rare and benign condition, which occurs when clearance of propofol exceeds the hepatic and extrahepatic elimination.

摘要

丙泊酚常用于麻醉诱导和维持以及重症监护病房的镇静。此外,它还被用作难治性癫痫持续状态的麻醉昏迷治疗。我们报告了一例52岁男性病例,该患者在接受丙泊酚昏迷治疗癫痫持续状态后出现绿色尿液。停止输注丙泊酚后尿液颜色恢复。尿液变绿是一种罕见的良性情况,当丙泊酚的清除超过肝脏和肝外清除时就会发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f6b/6374538/f60ac4926950/er-8-2-97f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f6b/6374538/f60ac4926950/er-8-2-97f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f6b/6374538/f60ac4926950/er-8-2-97f1.jpg

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本文引用的文献

1
Green Urine Due to Propofol: A Case Report with Review of Literature.丙泊酚导致的绿色尿液:一例病例报告并文献复习
J Clin Diagn Res. 2015 Nov;9(11):OD03-4. doi: 10.7860/JCDR/2015/15681.6706. Epub 2015 Nov 1.
2
Green Urine Discoloration due to Propofol Infusion: A Case Report.丙泊酚输注导致尿液变绿:一例报告
Case Rep Emerg Med. 2011;2011:242514. doi: 10.1155/2011/242514. Epub 2011 Dec 27.
3
Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit.
成人重症监护病房疼痛、躁动和谵妄管理的临床实践指南。
Crit Care Med. 2013 Jan;41(1):263-306. doi: 10.1097/CCM.0b013e3182783b72.
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Guidelines for the evaluation and management of status epilepticus.癫痫持续状态的评估和管理指南。
Neurocrit Care. 2012 Aug;17(1):3-23. doi: 10.1007/s12028-012-9695-z.
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Propofol induction resulting in green urine discoloration.丙泊酚诱导导致尿液变绿。
Anesthesiology. 2012 Apr;116(4):924. doi: 10.1097/ALN.0b013e31823a13bc.
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Dark green discoloration of the urine after prolonged propofol infusion: a case report.长时间输注丙泊酚后尿液呈暗绿色:一例报告。
J Clin Pharm Ther. 2011 Dec;36(6):734-6. doi: 10.1111/j.1365-2710.2010.01225.x. Epub 2010 Nov 17.
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On the Prevalence of Ankylostomiasis in St. Lucia and its Treatment.圣卢西亚钩虫病的患病率及其治疗
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Green urine.绿色尿液。
Lancet. 2009 Apr 25;373(9673):1462. doi: 10.1016/S0140-6736(09)60309-3.
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Propofol-related green urine.丙泊酚相关的绿色尿液。
Kidney Int. 2008 Oct;74(7):978. doi: 10.1038/ki.2008.139.