Department of Neurology, Myongji Hospital, Kwandong University College of Medicine, GyeongGi, Korea.
J Clin Pharm Ther. 2011 Dec;36(6):734-6. doi: 10.1111/j.1365-2710.2010.01225.x. Epub 2010 Nov 17.
Propofol, a commonly used sedative, has on rare occasions, been reported to discolour urine green. However, in previous reports, it is uncertain that whether this colour change is dose dependent. We report on a patient who produced dark green discoloration of urine from prolonged propofol infusion, administered for intractable epilepsy.
The colour intensity of the patient's urine was dependent on propofol infusion rate. Reducing propofol infusion rate lightened the colour of the urine, eventually back to normal.
Green discoloration of the urine from propofol infusion is dose dependent. It is usually benign and reversible, as was the case for our patient.
丙泊酚是一种常用的镇静剂，偶尔有报道称其会使尿液变绿。然而，在之前的报告中，尚不确定这种颜色变化是否与剂量有关。我们报告了一例因难治性癫痫而长时间输注丙泊酚导致尿液呈深绿色变色的患者。
患者尿液的颜色强度取决于丙泊酚输注率。降低丙泊酚输注率可使尿液颜色变浅，最终恢复正常。
丙泊酚输注引起的尿液绿色变色与剂量有关。就像我们的患者一样，这种情况通常是良性且可逆转的。
