母乳喂养与儿童习惯性打鼾风险：一项荟萃分析。
Breastfeeding and risk of habitual snoring in children: A meta-analysis.
机构信息
Department of Epidemiology and Health Statistics, The School of Public Health of Qingdao University, Qingdao, Shandong Province, China.
Department of Pharmacy, Qingdao No.6 People's Hospital, Qingdao, Shandong Province, China.
出版信息
Matern Child Nutr. 2019 Jul;15(3):e12799. doi: 10.1111/mcn.12799. Epub 2019 Mar 15.
Research regarding the effects of breastfeeding on habitual snoring in children has yielded conflicting results. Therefore, a meta-analysis was carried out to evaluate the effect of breastfeeding on the risk of habitual snoring in children. Relevant studies published in English or Chinese were identified by a search of PubMed, Embase, Web of Science, Chinese National Knowledge Infrastructure, China Biology Medical literature, and Wanfang databases up to October 2018. Random effects model was used to pool the findings, and results were expressed as odds ratios (OR) with 95% CIs. Eleven studies with 71,622 participants were included in the present meta-analysis. The pooled OR of habitual snoring for more versus less breastfeeding (duration) was 0.74 (95% CI [0.62, 0.90]), and the result remained significant in cohort studies (OR, 0.74; 95%CI [0.66, 0.84]). We found no evidence of publication bias. This meta-analysis of observational studies indicates that breastfeeding for a long time is associated with reduced risk of habitual snoring in children. The finding needs to be investigated in well-designed prospective studies.
关于母乳喂养对儿童习惯性打鼾影响的研究结果相互矛盾。因此，进行了荟萃分析，以评估母乳喂养对儿童习惯性打鼾风险的影响。通过检索 PubMed、Embase、Web of Science、中国国家知识基础设施、中国生物医学文献和万方数据库，截至 2018 年 10 月，确定了发表在英文或中文的相关研究。采用随机效应模型对研究结果进行合并，并以比值比（OR）及其 95%置信区间（95%CI）表示。本荟萃分析纳入了 11 项研究，共 71622 名参与者。习惯性打鼾的多 vs 少（持续时间）母乳喂养的汇总 OR 为 0.74（95%CI [0.62, 0.90]），队列研究的结果仍具有显著性（OR，0.74；95%CI [0.66, 0.84]）。我们未发现发表偏倚的证据。本观察性研究的荟萃分析表明，长时间母乳喂养与儿童习惯性打鼾风险降低相关。该发现需要在设计良好的前瞻性研究中进行进一步调查。
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