Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East-China University of Science and Technology, Shanghai 200237, China.
Analyst. 2019 Mar 25;144(7):2411-2415. doi: 10.1039/c9an00010k.
An electrodialytic methanesulfonic acid (MSA) generator with a two-membrane configuration is described for ion chromatography (IC). It is fabricated by using a stacked anion exchange membrane (sAEM) and a bipolar membrane (BPM) plus stacked sAEMs (BPM-sAEM) to respectively isolate the central eluent channel from two outer regenerant chambers bearing the MSA feed solution. The cation exchange membrane (CEM) side of a BPM is facing the central channel (the cathode direction) and the sAEM is at the cathode side with respect to the anode of the BPM-sAEM side. Under an electric field, the hydronium ion produced at the junction layer of BPM via enhanced water splitting will electromigrate through CEM associated with BPM into the central channel, meanwhile methanesulfonate from the MSA feed solution at the cathode migrates into the central channel to combine with the hydronium ion together to form a solution of MSA. Such a device can produce a gas-free MSA eluent and no gas removal device is required. The produced MSA concentration was highly dependent on the applied current and up to at least 60.5 mM MSA could be produced. The device showed good running stability, as indicated by the retention time of RSD 0.15% and the peak area of RSD 1.7%.
一种具有双膜结构的电渗析甲磺酸（MSA）发生器，用于离子色谱（IC）。它是通过使用堆叠阴离子交换膜（sAEM）和双极膜（BPM）加堆叠 sAEM（BPM-sAEM）来分别将中央洗脱液通道与两个承载 MSA 进料溶液的外部再生室隔离开来制造的。BPM 的阳离子交换膜（CEM）侧面向中央通道（阴极方向），sAEM 位于 BPM-sAEM 侧的阳极的阴极侧。在电场作用下，通过增强水分解在 BPM 的结层中产生的氢离子将通过 CEM 与 BPM 一起电迁移到中央通道，同时来自阴极的 MSA 进料溶液中的甲磺酸盐迁移到中央通道与氢离子结合在一起形成 MSA 溶液。这样的装置可以产生无气体的 MSA 洗脱液，不需要气体去除装置。所产生的 MSA 浓度高度依赖于施加的电流，至少可以产生 60.5mM 的 MSA。该装置表现出良好的运行稳定性，保留时间的 RSD 为 0.15%，峰面积的 RSD 为 1.7%。
