Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong RD, Shanghai 200237, China.
Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong RD, Shanghai 200237, China.
J Chromatogr A. 2020 Jul 5;1622:461095. doi: 10.1016/j.chroma.2020.461095. Epub 2020 Apr 20.
A two-membrane electrodialytic carbonate eluent generator (EDG) for ion chromatography (IC) is described. It is in a sandwich-like configuration, in which the central eluent channel is spatially isolated from two outer regenerant channels by stacked cation exchange membranes (CEMs) and anion exchange membranes (AEMs). A platinum screen electrode is placed in each of two outer regenerant channels. The electrode at the CEMs side is set as an anode with respect to the electrode at the AEMs side being cathode. Potassium carbonate and/or bicarbonate solution is pumped into the regenerant channel as feed solution. The electromigration of carbonate and/or bicarbonate and potassium from feed solution respectively through AEMs and CEMs will form a gas-free eluent. With this configuration, ion transport behavior through AEMs was explored. The device demonstrated good reproducibility, as indicated by the relative standard deviation of retention time of less than 0.08%.
一种用于离子色谱（IC）的双层电渗析碳酸洗脱液发生器（EDG）。它呈三明治状结构，其中中央洗脱液通道通过堆叠的阳离子交换膜（CEM）和阴离子交换膜（AEM）与两个外部再生剂通道在空间上隔离。在两个外部再生剂通道中的每一个中都放置一个铂筛电极。相对于设置在 AEM 侧的电极作为阴极，CEM 侧的电极被设置为阳极。碳酸钾和/或碳酸氢钾溶液作为进料溶液被泵入再生剂通道。碳酸根和/或碳酸氢根以及钾通过 AEM 和 CEM 分别从进料溶液中的电迁移将形成无气体的洗脱液。通过这种配置，研究了离子通过 AEM 的传输行为。该装置表现出良好的重现性，保留时间的相对标准偏差小于 0.08%。
