Leu H J, Makek M
Cancer. 1986 Apr 1;57(7):1395-400. doi: 10.1002/1097-0142(19860401)57:7<1395::aid-cncr2820570726>3.0.co;2-o.
Five cases of intramural venous leiomyosarcomas are described. Only one was localized in the inferior vena cava, the classic site; the other four cases were situated in smaller veins, namely, the short and long saphenous veins, the external jugular vein, and a superficial vein at the back of the hand. Light and, in two cases, electron microscopy, as well as immunohistochemical examinations for factor VIII, helped to establish the diagnosis. The fate of these cases indicates that size and localization are the main determining factors of outcome, whereas the level of mitotic activity is informative only if it is high. Small tumors in superficial veins that are detected early may have an excellent prognosis, even after limited removal of the tumor.
本文描述了5例壁内静脉平滑肌肉瘤。仅1例位于下腔静脉这一经典部位，其他4例位于较小的静脉，即大隐静脉、小隐静脉、颈外静脉和手背的一条浅静脉。光镜检查以及其中2例的电镜检查，还有针对因子VIII的免疫组化检查，均有助于确诊。这些病例的转归表明，肿瘤大小和部位是决定预后的主要因素，而有丝分裂活性水平只有在很高时才有参考价值。早期发现的浅表静脉小肿瘤，即使肿瘤切除范围有限，预后也可能很好。
