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Ag/AgCl 修饰的无水碱式硝酸铋的合成及其抗菌活性。

Synthesis of Ag/AgCl modified anhydrous basic bismuth nitrate from BiOCl and the antibacterial activity.

机构信息

College of Materials Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300192, China.

出版信息

Mater Sci Eng C Mater Biol Appl. 2019 May;98:83-88. doi: 10.1016/j.msec.2018.12.116. Epub 2018 Dec 28.

Abstract

Novel nanocomposite of Ag/AgCl and a single phase of anhydrous basic bismuth nitrate (ABBN)-BiO(OH)(NO) with efficient antibacterial activity was prepared from BiOCl. Microstructure was characterized as AgCl nanotubes and Ag nanoparticles mixed with BiO(OH)(NO) nanosheets in nanometer scale. Antibacterial activity of the composite was tested by agar disc diffusion and agar dilution methods using Escherichia coli as target bacteria. The diameter of inhibition zone of Ag/AgCl/ABBN is 17.0 mm while that of bulk BBN is 8.1 mm. The MIC value of Ag/AgCl/ABBN is ascertained as 35 μg mL. Results prove that Ag/AgCl/ABBN nanocomposite has much higher antibacterial activity in comparison with bulk basic bismuth nitrate.

摘要

新型纳米复合材料 Ag/AgCl 和单相无水碱式硝酸铋(ABBN)-BiO(OH)(NO) 具有高效的抗菌活性,由 BiOCl 制备。微观结构特征为纳米级 AgCl 纳米管和 Ag 纳米颗粒与 BiO(OH)(NO) 纳米片混合。采用琼脂圆盘扩散和琼脂稀释法,以大肠杆菌为靶细菌,测试了复合材料的抗菌活性。Ag/AgCl/ABBN 的抑菌圈直径为 17.0mm,而块状 BBN 的抑菌圈直径为 8.1mm。Ag/AgCl/ABBN 的 MIC 值确定为 35μgmL。结果表明,与块状碱式硝酸铋相比,Ag/AgCl/ABBN 纳米复合材料具有更高的抗菌活性。

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