Faculty of Medicine, University of Southampton, Southampton, UK.
Orthopaedic Surgery, University Hospital Southampton, Southampton, UK.
Bone Joint J. 2019 Mar;101-B(3):281-287. doi: 10.1302/0301-620X.101B3.BJJ-2018-1331.R1.
The aim of this study was to establish the incidence of developmental dysplasia of the hip (DDH) diagnosed after one-year of age in England, stratified by age, gender, year, and region of diagnosis.
A descriptive observational study was performed by linking primary and secondary care information from two independent national databases of routinely collected data: the United Kingdom Clinical Practice Research Datalink and Hospital Episode Statistics. The study examined all children from 1 January 1990 to 1 January 2016 who had a new first diagnostic code for DDH aged between one and eight years old.
The incidence of late-diagnosed DDH was 1.28 per 1000 live births. Within the study population, 754 children were identified with a diagnosis of DDH after one-year of age. Of all late diagnoses, 536 (71.1%) were detected between one to two years of age. There were 608 female patients (80.6%) and 146 male patients (19.4%), giving a female-to-male ratio of 4.2:1. Distribution was evenly spread throughout England.
The incidence of late-diagnosed DDH has not been reduced from that reported 35 years ago, prior to the introduction of the national selective screening programme for DDH. Cite this article: Bone Joint J 2019;101-B:281-287.
本研究旨在确定英国一岁后确诊的发育性髋关节发育不良（DDH）的发病率，并按年龄、性别、年份和诊断区域进行分层。
通过将两个独立的常规收集数据的国家数据库（英国临床实践研究数据链接和医院发病统计数据）中的初级和二级护理信息进行链接，开展了一项描述性观察研究。该研究共纳入了 1990 年 1 月 1 日至 2016 年 1 月 1 日期间年龄在 1 至 8 岁之间、新诊断出患有 DDH 的所有儿童。
晚发型 DDH 的发病率为每 1000 例活产儿 1.28 例。在研究人群中，有 754 名儿童在一岁后被诊断出患有 DDH。在所有晚诊病例中，有 536 例（71.1%）在 1 至 2 岁之间被发现。其中 608 例为女性患者（80.6%），146 例为男性患者（19.4%），女性与男性之比为 4.2:1。分布在英格兰各地均匀。
在引入 DDH 全国选择性筛查计划之前，即 35 年前，晚发型 DDH 的发病率并未降低。
