Citti Cinzia, Linciano Pasquale, Panseri Sara, Vezzalini Francesca, Forni Flavio, Vandelli Maria Angela, Cannazza Giuseppe
Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
CNR NANOTEC, Institute of Nanotechnology, Lecce, Italy.
Front Plant Sci. 2019 Feb 13;10:120. doi: 10.3389/fpls.2019.00120. eCollection 2019.
Hemp seed oil is well known for its nutraceutical, cosmetic and pharmaceutical properties due to a perfectly balanced content of omega 3 and omega 6 polyunsaturated fatty acids. Its importance for human health is reflected by the success on the market of organic goods in recent years. However, it is of utmost importance to consider that its healthy properties are strictly related to its chemical composition, which varies depending not only on the manufacturing method, but also on the hemp variety employed. In the present work, we analyzed the chemical profile of ten commercially available organic hemp seed oils. Their cannabinoid profile was evaluated by a liquid chromatography method coupled to high-resolution mass spectrometry. Besides tetrahydrocannabinol and cannabidiol, other 30 cannabinoids were identified for the first time in hemp seed oil. The results obtained were processed according to an untargeted metabolomics approach. The multivariate statistical analysis showed highly significant differences in the chemical composition and, in particular, in the cannabinoid content of the hemp oils under investigation.
由于富含完美平衡的ω-3和ω-6多不饱和脂肪酸，大麻籽油以其营养保健、美容和药用特性而闻名。近年来有机产品在市场上的成功反映了其对人类健康的重要性。然而，至关重要的是要考虑到其健康特性与其化学成分密切相关，化学成分不仅取决于制造方法，还取决于所使用的大麻品种。在本研究中，我们分析了十种市售有机大麻籽油的化学特征。通过液相色谱法与高分辨率质谱联用对其大麻素特征进行了评估。除了四氢大麻酚和大麻二酚外，首次在大麻籽油中鉴定出其他30种大麻素。所得结果按照非靶向代谢组学方法进行处理。多元统计分析表明，所研究的大麻籽油在化学成分上，特别是在大麻素含量上存在高度显著差异。
