Choi Seung-Hyun, Kim Hui-Yun, Oh Seon-Min, Bae Ji-Eun, Ye Sang-Jin, Park Young Joon, Kim Byung-Yong, Baik Moo-Yeol
1Department of Food Science and Biotechnology, Institute of Life Science and Resources, Kyung Hee University, Yongin, Republic of Korea.
2Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Yongin, Republic of Korea.
Food Sci Biotechnol. 2018 Aug 22;28(1):99-102. doi: 10.1007/s10068-018-0455-5. eCollection 2019 Feb.
The objective of this study was to develop new drug delivery systems (DDS) and nutrient delivery systems (NDS), using starch as a carrier material for infusion technology. Corn, waxy rice, non-waxy rice, and potato starches were used as carrier materials. Sodium fluorescein was used as an infusion material for easy detection. Each starch suspension with sodium fluorescein was reacted in a water bath at 40, 50, and 60 °C for 30 min. After each reaction, the concentration of sodium fluorescein in the supernatant was measured using a fluorescence detector. Precipitated starch was observed using fluorescence microscopy. About 70% of sodium fluorescein infused in waxy rice and corn starches at 60 °C. Additionally, the granules of these two starches were luminous by green light when exposed to a fluorescence detector, suggesting that corn and waxy rice starches can be used as carrier materials in infusion technology for DDS and NDS.
本研究的目的是开发新的药物递送系统(DDS)和营养递送系统(NDS),使用淀粉作为输液技术的载体材料。玉米淀粉、糯米淀粉、非糯米淀粉和马铃薯淀粉被用作载体材料。荧光素钠用作输液材料以便于检测。将每种含有荧光素钠的淀粉悬浮液在40、50和60℃的水浴中反应30分钟。每次反应后,使用荧光检测器测量上清液中荧光素钠的浓度。使用荧光显微镜观察沉淀的淀粉。在60℃时,约70%的荧光素钠注入了糯米淀粉和玉米淀粉中。此外,当暴露于荧光检测器时,这两种淀粉的颗粒发出绿光,表明玉米淀粉和糯米淀粉可作为输液技术中DDS和NDS的载体材料。