Özçınar Beyza, Güler Sertaç Ata, Kocaman Nazmiye, Özkan Mine, Güllüoğlu Bahadır M, Özmen Vahit
Department of General Surgery, Istanbul University Istanbul School of Medicine, İstanbul, Turkey.
Department of General Surgery, Marmara University School of Medicine, İstanbul, Turkey.
Eur J Breast Health. 2018 Oct 24;15(1):51-58. doi: 10.5152/ejbh.2018.4198. eCollection 2019 Jan.
Aim of this prospective study was to determine the complications of different treatment modalities for breast cancer and assess their impact on patients' quality-of-life and psychological status.
Patients surgically treated for early-stage breast cancer were enrolled in the study. Complications after treatment and quality-of-life parameters were measured and recorded.
218 patients, all female with a median age of 48 (19-82) years, were included in the study. In early period, significant limitation of shoulder movements, increased pain and decreased in functional capacity were observed, whereas in mid-term, all shoulder movements, as well as pain and functional capacity returned normal. In both early period and mid-terms, anxiety scores were significantly decreased, whereas depression scores were significantly increased. In early period, there was a significant decrease in physical and mental area scores. Social area scores were significantly increased, whereas environmental, mental and physical area scores were significantly decreased in mid-term and late period.
Overall, patients' quality-of-life was found to be significantly deteriorated in both early period and mid-term and returned to pre-treatment period at long term follow up.
本前瞻性研究旨在确定乳腺癌不同治疗方式的并发症，并评估其对患者生活质量和心理状态的影响。
纳入接受早期乳腺癌手术治疗的患者。测量并记录治疗后的并发症及生活质量参数。
本研究共纳入218例患者，均为女性，中位年龄48（19 - 82）岁。早期观察到肩部活动明显受限、疼痛加剧及功能能力下降，而中期所有肩部活动、疼痛及功能能力均恢复正常。早期和中期焦虑评分均显著降低，而抑郁评分显著升高。早期身体和心理领域评分显著降低。社会领域评分显著升高，而中期和后期环境、心理和身体领域评分显著降低。
总体而言，患者生活质量在早期和中期均显著恶化，长期随访时恢复至治疗前水平。
