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直线加速器输出测量的季节性变化。

Seasonal variations in measurements of linear accelerator output.

作者信息

Bartolac Steven, Heaton Robert, Norrlinger Bernhard, Letourneau Daniel

机构信息

Radiation Medicine Program, Princess Margaret Cancer Center, Toronto, ON, Canada.

Radiation Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA.

出版信息

J Appl Clin Med Phys. 2019 Mar;20(3):81-88. doi: 10.1002/acm2.12548. Epub 2019 Feb 28.

Abstract

PURPOSE

Seasonal trends in linear accelerator output have been reported by at least one institution and data have suggested that they may be present at our center as well. The purpose of this work was to characterize these trends and determine whether local environmental conditions within the treatment rooms may be impacting the linear accelerators and/or the quality control (QC) dosimeter.

METHODS

Runtime plots of daily output data, acquired using an in-house ion chamber-based device, over 3 yr and for 15 linear accelerators of different makes and models were reviewed and evaluated. Environmental conditions were monitored prospectively in a representative treatment room for approximately 9 months and evaluated for correlations with output trends. Independent measures of output using daily MV portal images were compared with output measurements using the ion chamber-based device. A separate controlled experiment probing the response of the in-house dosimeter to humidity changes over time was also carried out using a constant current source and a small enclosure.

RESULTS

Runtime plots of output revealed sinusoidal, seasonal variations that were consistent across all treatment units, irrespective of manufacturer, model, or age of machine. The amplitude of the variation was on the order of 1% and maintained a yearly period. The independent measure of output using MV portal images did not corroborate the seasonal trends observed with the daily QC dosimeter. Based on the controlled experiment, the QC dosimeter was found to have a dependence on relative humidity changes, decreasing 1% in output per 30% increase in relative humidity.

CONCLUSIONS

Results confirm the presence of underlying seasonal variations in measured output from the linear accelerators. The findings identify humidity impact on the measurement device as the underlying cause of the cyclical changes and not the accelerators themselves. These results could help minimize unwarranted machine servicing.

摘要

目的

至少有一家机构报告了直线加速器输出的季节性趋势,数据表明我们中心可能也存在这种趋势。这项工作的目的是描述这些趋势,并确定治疗室内的局部环境条件是否可能影响直线加速器和/或质量控制(QC)剂量计。

方法

回顾并评估了使用内部基于电离室的设备在3年时间内获取的15台不同品牌和型号直线加速器的每日输出数据的运行图。在一个有代表性的治疗室中对环境条件进行了约9个月的前瞻性监测,并评估其与输出趋势的相关性。将使用每日兆伏级射野图像进行的输出独立测量结果与使用基于电离室的设备进行的输出测量结果进行比较。还使用恒流源和一个小的封闭空间进行了一项单独的对照实验,以探究内部剂量计对湿度随时间变化的响应。

结果

输出的运行图显示出正弦形的季节性变化,所有治疗单元的变化都是一致的,与制造商、型号或机器使用年限无关。变化幅度约为1%,且周期为一年。使用兆伏级射野图像进行的输出独立测量结果并未证实每日QC剂量计所观察到的季节性趋势。基于对照实验,发现QC剂量计对相对湿度变化有依赖性,相对湿度每增加30%,输出降低1%。

结论

结果证实直线加速器测量输出中存在潜在的季节性变化。研究结果确定湿度对测量设备的影响是周期性变化的根本原因,而不是加速器本身。这些结果有助于尽量减少不必要的机器维修。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1794/6414147/d7592bb05a54/ACM2-20-81-g001.jpg

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