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Severe ketoacidosis as the first manifestation of diabetes mellitus after age fifty.

作者信息

Peter S A

出版信息

J Natl Med Assoc. 1986 Feb;78(2):148-50.

Abstract

Two women over the age of 50 years presented with ketoacidosis as the first manifestation of diabetes mellitus. The first patient failed to respond to a regimen of hourly intramuscular injections of regular insulin. She only improved when a continuous intravenous infusion of regular insulin was utilized. The second patient was treated with a continuous infusion of insulin for a prolonged period. Her course was uneventful. It is recommended that a regimen of continuous infusion of regular insulin be the treatment of choice in the management of older patients presenting with ketoacidosis at the time of diagnosis of diabetes mellitus.

摘要

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本文引用的文献

1
Insulin resistance in diabetic ketoacidosis.
Diabetes. 1982 Oct;31(10):923-8. doi: 10.2337/diab.31.10.923.
4
The efficacy of low-dose versus conventional therapy of insulin for treatment of diabetic ketoacidosis.
Ann Intern Med. 1976 Jun;84(6):633-8. doi: 10.7326/0003-4819-84-6-633.
5
Glucose intolerance and aging: evidence for tissue insensitivity to insulin.
Diabetes. 1979 Dec;28(12):1095-101. doi: 10.2337/diab.28.12.1095.
7
Current views on the etiology of insulin-dependent diabetes mellitus.
N Engl J Med. 1978 Dec 28;299(26):1439-45. doi: 10.1056/NEJM197812282992605.

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