Dooley D M
Neurosurgery. 1977 Sep-Oct;1(2):220-4. doi: 10.1097/00006123-197709000-00026.
Fifty per cent of patients diagnosed as having multiple sclerosis, primary lateral sclerosis, or hereditary spinocerebellar disorders were observed to have enduring favorable changes in neurological function during the 15 to 27 months they have been followed. The patients who were the least severely disabled were benefitted the most by the stimulation and made the most rapid progress. For example, the patient having only an ataxic or a spastic gait typically was observed to improve faster than the patient having both an ataxic and a spastic gait. The long term effect of electrostimulation of the spinal cord on these patients is unknown. The purpose of the stimulation is to attempt to obtain an improvement in neurological function so that the patient may experience a better life style. It is not thought that the electrical current has any effect on the basic disease process. Electrostimulation over the posterior spinal roots and spinal cord, although not new, has not been used extensively for the treatment of patients with arterial disease. The patients who have responded the most dramatically to electrostimulation are those with vasospastic disorders. A larger percentage of patients showed a greater response to implanted stimulation than to transcutaneous stimulation. Electrostimulation of the nervous system is not designed to replace standard therapeutic measures of treatment of patients with vascular disease, but to supplement them.
在对被诊断患有多发性硬化症、原发性侧索硬化症或遗传性脊髓小脑疾病的患者进行的15至27个月随访中，观察到50%的患者神经功能有持续的良好变化。残疾程度最轻的患者从这种刺激中受益最大，进步也最快。例如，通常观察到仅患有共济失调或痉挛性步态的患者比同时患有共济失调和痉挛性步态的患者改善得更快。脊髓电刺激对这些患者的长期影响尚不清楚。刺激的目的是试图改善神经功能，以便患者能体验更好的生活方式。人们认为电流对基本疾病进程没有任何影响。脊髓后根和脊髓的电刺激虽然不是新技术，但尚未广泛用于治疗动脉疾病患者。对电刺激反应最显著的患者是患有血管痉挛性疾病的患者。与经皮刺激相比，更大比例的患者对植入式刺激表现出更大的反应。神经系统电刺激并非旨在取代血管疾病患者的标准治疗措施，而是对其进行补充。
