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针对患有神经系统脱髓鞘和退行性疾病以及四肢血管疾病的患者进行神经系统电刺激。

Electrostimulation of the nervous system for patients with demyelinating and degenerative diseases of the nervous system and vascular diseases of the extremities.

作者信息

Dooley D M, Sharkey J

出版信息

Appl Neurophysiol. 1977;40(2-4):208-17. doi: 10.1159/000102444.

Abstract

The results of electrostimulation of the spinal cord for symptoms other than that of pain are recorded in this publication. 50% of patients with multiple sclerosis, primary lateral sclerosis and hereditary spino-cerebellar disorders were observed to have enduring favourable changes in neurological function during the 15 to 27 months they have been followed. The patients who were the least severely disabled had the greatest amount of increased function and were benefitted the most by the stimulation. Those who had the fewest neurological pathways affected make the most rapid progress. For example, the patient with only an ataxic or spastic gait was observed to improve faster than the patient with an ataxic and a spastic gait. The long-term effect of electrostimulation of the spinal cord on patients with these diseases is unknown at the present time. The purpose of the stimulation is to increase neurological function so that the patient can live a better life style. It is not thought that the electrical current is responsible for a 'cure' of the basic disease process. Electrostimulation of the posterior spinal roots and spinal cord, while not new, has not been used extensively for the treatment of patients with arterial disease. The patients who have responded the most dramatically to electrostimulation are those with vasospastic disorders. A larger percentage of patients showed a greater response to implanted stimulation than to transcutaneous stimulation. Electrostimulation of the nervous system is not designed to replace standard therapeutic measures of treatment of patients with vascular disease but to supplement them.

摘要

本出版物记录了脊髓电刺激治疗疼痛以外症状的结果。在对患有多发性硬化症、原发性侧索硬化症和遗传性脊髓小脑疾病的患者进行的15至27个月的随访中,观察到50%的患者神经功能有持久的良好变化。残疾程度最轻的患者功能增加最多,且从刺激中获益最大。受神经通路影响最少的患者进步最快。例如,仅患有共济失调或痉挛步态的患者比同时患有共济失调和痉挛步态的患者改善得更快。目前,脊髓电刺激对这些疾病患者的长期影响尚不清楚。刺激的目的是增强神经功能,使患者能够过上更好的生活方式。人们认为电流并不能“治愈”基本的疾病进程。脊髓后根和脊髓的电刺激虽然不是新技术,但尚未广泛用于治疗动脉疾病患者。对电刺激反应最显著的患者是患有血管痉挛性疾病的患者。与经皮刺激相比,更大比例的患者对植入式刺激表现出更大的反应。神经系统电刺激并非旨在取代血管疾病患者的标准治疗措施,而是对其进行补充。

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