Shioji Naohiro, Kanazawa Tomoyuki, Iwasaki Tatsuo, Shimizu Kazuyoshi, Suemori Tomohiko, Kuroe Yasutoshi, Morimatsu Hiroshi
Department of Anesthesiology and Resuscitology, Okayama University Hospital, Okayama 700-8558, Japan.
Acta Med Okayama. 2019 Feb;73(1):15-20. doi: 10.18926/AMO/56454.
We compared the reintubation rate in children who received high-flow nasal cannula (HFNC) therapy to the rate in children who received noninvasive ventilation (NIV) therapy for acute respiratory failure (ARF) after cardiac surgery. This was a retrospective analysis of 35 children who received HFNC therapy for ARF after cardiac surgery in 2014-2015 (the HFNC group). We selected 35 children who had received NIV therapy for ARF after cardiac surgery in 2009-2012 as a control group. The matching parameters were body weight and risk adjustment for congenital heart surgery category 1. The reintubation rate within 48 h in the HFNC group tended to be lower than that in the NIV group (3% vs. 17%, p=0.06). The reintubation rate within 28 days was significantly lower in the HFNC group compared to the NIV group (3% vs. 26%, p=0.04). The HFNC group's ICU stays were significantly shorter than those of the NIV group: 10 (IQR: 7-17) days vs. 17 (11-32) days, p=0.009. HFNC therapy might be associated with a reduced reintubation rate in children with ARF after cardiac surgery.
我们比较了接受高流量鼻导管（HFNC）治疗的儿童与接受无创通气（NIV）治疗的心脏手术后急性呼吸衰竭（ARF）儿童的再次插管率。这是一项对2014 - 2015年心脏手术后因ARF接受HFNC治疗的35名儿童（HFNC组）的回顾性分析。我们选择了2009 - 2012年心脏手术后因ARF接受NIV治疗的35名儿童作为对照组。匹配参数为体重和先天性心脏病手术1类的风险调整。HFNC组48小时内的再次插管率倾向于低于NIV组（3%对17%，p = 0.06）。HFNC组28天内的再次插管率显著低于NIV组（3%对26%，p = 0.04）。HFNC组的重症监护病房住院时间显著短于NIV组：10（四分位间距：7 - 17）天对17（11 - 32）天，p = 0.009。HFNC治疗可能与心脏手术后ARF儿童再次插管率降低有关。
